A Comparative Analysis of Oocyte Development in Mammals
2020
Dalbies-Tran, Rozenn | Cadoret, Véronique | Desmarchais, Alice | Elis, Sébastien | Maillard, Virginie | Monget, Philippe | Monniaux, Danielle | Reynaud, Karine | Saint-Dizier, Marie | Uzbekova, Svetlana | Physiologie de la reproduction et des comportements [Nouzilly] (PRC) ; Institut Français du Cheval et de l'Equitation [Saumur] (IFCE)-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | CHU Bretonneau, Médecine et Biologie de la Reproduction-CECOS,
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Mostrar más [+] Menos [-]Inglés. Sexual reproduction requires the fertilization of a female gamete after it has undergone optimal development. Various aspects of oocyte development and many molecular actors in this process are shared among mammals, but phylogeny and experimental data reveal species specificities. In this chapter, we will present these common and distinctive features with a focus on three points: the shaping of the oocyte transcriptome from evolutionarily conserved and rapidly evolving genes, the control of folliculogenesis and ovulation rate by oocyte-secreted Growth and Differentiation Factor 9 and Bone Morphogenetic Protein 15, and the importance of lipid metabolism.
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