Coenzyme Synthesis in Plant Mitochondria
2006
Ravanel, Stéphane | Alban, Claude | Rébeillé, Fabrice | Laboratoire de physiologie cellulaire végétale (LPCV) ; Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Recherche Agronomique (INRA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG) ; Direction de Recherche Fondamentale (CEA) (DRF (CEA)) ; Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)) ; Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA) | Lincoln Taiz and Eduardo Zeiger | Lincoln Taiz | Eduardo Zeiger
Open Access article: http://4e.plantphys.net/article.php?ch=11&id=358
Mostrar más [+] Menos [-]Inglés. The synthesis of many biological compounds and the regulation of several metabolic processes require the addition or removal of one-carbon units (C1-units). Tetrahydrofolate derivatives (vitamin B9) mediate most of these transfers of C1-units, directly or indirectly, via S-adenosylmethionine. Some enzymes involved in CO2 manipulation during carboxylation, decarboxylation, and transcarboxylation reactions utilize another essential cofactor, biotin (vitamin B8). Unlike plants and some fungi and bacteria, mammals cannot synthesize tetrahydrofolate or biotin de novo and depend entirely on their dietary supply. The aim of the present Essay is to summarize recent progress in elucidating the tetrahydrofolate and biotin biosynthetic pathways in plants, with an emphasis on the essential role of mitochondria in these complex networks.
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