Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons
2016
Burke, Luke K. | Doslikova, Barbora | D'Agostino, Giuseppe | Greenwald-Yarnell, Megan | Georgescu, Teodora | Chianese, Raffaella | Martinez de Morentin, Pablo B. | Ogunnowo-Bada, Emmanuel | Cansell, Celine | Valencia-Torres, Lourdes | Garfield, Alastair S. | Apergis-Schoute, John | Lam, Daniel D. | Speakman, John R. | Rubinstein, Marcelo | Low, Malcolm J. | Rochford, Justin J. | Myers, Martin G. | Evans, Mark L. | Heisler, Lora K. | University of Aberdeen.Rowett Institute | University of Aberdeen.Institute of Applied Health Sciences | University of Aberdeen.Biological Sciences | University of Aberdeen.Environment and Food Security | University of Aberdeen.Energetics Research Group
Acknowledgments Work was supported by the Wellcome Trust (WT098012; WT081713) and Biotechnology and Biological Sciences Research Council (BB/K001418/1) to LKH, Wellcome Trust (093566/Z/10/A) to LKB/LKH, the Diabetes UK (13/0004680) to MLE, the Genomics/Transcriptomics core, Disease Model Core, Bespoke Mouse Models, Imaging, Proteomics Wellcome Trust Strategic Award [100574/Z/12/Z] and Genomics/Transcriptomics Core Facilities, Disease Model Core, CBAL MRC Metabolic Diseases Unit [MRC_MC_UU_12012/5] to LKH, MLE, BD and LKB, the Neuroscience Graduate Program, University of Michigan to MG-Y, the National Institute of Health (DK066604) to MJL and (DK068400) to MJL and MR, and National Institute of Health (DK056731) and the Marilyn H. Vincent Foundation to MGM. The University of Michigan Transgenic Core facility is partially supported by the NIH-funded University of Michigan Center for Gastrointestinal Research (DK034933). The authors would like to thank Dr Samuel Virtue for technical training in BAT lipid accumulation quantification.
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