Enhancing in vitro biocompatibility and corrosion protection of organic-inorganic hybrid sol-gel films with nanocrystalline hydroxyapatite
2014
El Hadad, Amir A. | Barranco, Violeta | Jiménez-Morales, Antonia | Peón, Eduardo | Hickman, G. J. | Perry, C. C. | Galván Sierra, Juan Carlos
Application of novel organic-inorganic hybrid sol-gel coatings containing dispersed hydroxyapatite (HAp) particles improves the biocompatibility, normal human osteoblast (NHOst) response in terms of osteoblast viability and adhesion of a Ti6Al4V alloy routinely used in medical implants. The incorporation of HAp particles additionally results in more effective barrier proprieties and improved corrosion protection of the Ti6Al4V alloy through higher degree of cross-linking in the organopolysiloxane matrix and enhanced film thickness. This journal is © the Partner Organisations 2014.
Mostrar más [+] Menos [-]This work was supported by the Spanish Ministry of Economy and Competitivity (Project MAT2012-30854). A. A. El hadad acknowledges a pre-doctoral contract JAE financed by CSIC and the Interdisciplinary Biomedical Research Centre at NTU University. V. Barranco acknowledges a Ramon y Cajal researcher contract financed by CSIC-MINECO. GJH and CCP acknowledge support of the John van Geest Cancer Research Centre and RAE funding in support of work performed at NTU.
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