Comparison of immunosuppression in dry and lactating Awassi ewes due to water deprivation stress
2005
Barbour E. | Rawda N. | Banat G. | Jaber L. | Sleiman F.T. | Hamadeh S. | Barbour, E., Department of Animal Science, Fac. of Agricultural-Food Sciences, American University of Beirut, PO Box 11, 0236 Beirut, Lebanon | Rawda, N., Department of Animal Science, Fac. of Agricultural-Food Sciences, American University of Beirut, PO Box 11, 0236 Beirut, Lebanon | Banat, G., Department of Animal Science, Fac. of Agricultural-Food Sciences, American University of Beirut, PO Box 11, 0236 Beirut, Lebanon | Jaber, L., Department of Animal Science, Fac. of Agricultural-Food Sciences, American University of Beirut, PO Box 11, 0236 Beirut, Lebanon | Sleiman, F.T., Department of Animal Science, Fac. of Agricultural-Food Sciences, American University of Beirut, PO Box 11, 0236 Beirut, Lebanon | Hamadeh, S., Department of Animal Science, Fac. of Agricultural-Food Sciences, American University of Beirut, PO Box 11, 0236 Beirut, Lebanon | Barbour, E.; Department of Animal Science, Fac. of Agricultural-Food Sciences, American University of Beirut, PO Box 11, 0236 Beirut, Lebanon; email: [email protected] | University: American University of Beirut; Faculty: Faculty of Agricultural and Food Sciences; Department: Animal and Veterinary Sciences; | Animal and Veterinary Sciences | [email protected] | Faculty of Agricultural and Food Sciences | Barbour, E | Rawda, N | Banat, G | Jaber, L | Sleiman, FT | Hamadeh, S | Barbour, E (reprint author), Amer Univ Beirut, Fac Agr and Food Sci, Dept Anim Sci, POB 11-0236, Beirut, Lebanon. | barbour, elie-P-6166-2014 | American University of Beirut
In seminomadic farming practice, dry and lactating ewes are exposed to different degrees of water deprivation, leading to stress followed by various disease outbreaks. This study compares quantitatively the immunosuppression to Salmonella Enteritidis (SE) fimbriae (14 and 21 kDa) and other major polypeptides (28.9, 37.7, 42.9, 68.0, 92.6 and 96.8 kDa) in water-deprived dry and lactating ewes. Sixteen dry and lactating multiparous Awassi ewes were divided into four treatment groups (A, A′, B and B′). Ewes in groups A and B were lactating, whereas ewes in groups A′ and B′ were dry. All ewes were administered a killed SE vaccine, subcutaneously in the neck, at the initiation of the experiment. The water availability for ewes in groups B (lactating) and B′ (dry) was ad libitum, while that for ewes in groups A (lactating) and A′ (dry) was once every 4 days. A serum sample was collected from the jugular vein of each ewe at zero time (initiation of the experiment, when SE bacterin was delivered) and at 2, 9, 12, 15 and 18 days post SE vaccination. The percentage reduction in the level of humoral antibody response to polypeptides of ≥21 kDa was more apparent in water-deprived lactating ewes of group A between 9 and 18 days post initiation of thirst. In this period, immunosuppression to polypeptides ≥21 kDa was present in 14 out of 16 observations in group A (water-deprived lactating), with significant immunosuppression in 9 observations in relation to the respective control (p0.05), while it was present in only 4 out of 16 observations in group A′ (water-deprived dry), with significant immunosuppression in 2 observations (p0.05). In conclusion, immunosuppression to polypeptides of ≥21 kDa is more significant in lactating water-deprived ewes in the period 9-18 days post initiation of thirst, a result that will influence our future sheep welfare awareness programmes targeting an elimination of the practice of water deprivation in seminomadic sheep farming. © 2005 Springer.
Mostrar más [+] Menos [-]ASLANZADEH J, 1992, MICROBIOL IMMUNOL, V36, P351; AUSTYN JM, 1993, PRINCIPLES CELLULAR, P437; Barbour EK, 1996, SMALL RUMINANT RES, V21, P239, DOI 10.1016-0921-4488(95)00836-5; Barbour EK, 2000, J VET MED SCI, V62, P565, DOI 10.1292-jvms.62.565; Barbour EK, 2000, J VET MED SCI, V62, P1139, DOI 10.1292-jvms.62.1139; BARBOUR EK, 1993, AM J VET RES, V54, P1306; CDC, 1993, MMWR-MORBID MORTAL W, V42, P793; CHART H, 1989, FEMS MICROBIOL LETT, V58, P299, DOI 10.1016-0378-1097(89)90057-8; CHEN P, 1976, INT J PARASITOL, V6, P135, DOI 10.1016-0020-7519(76)90070-9; COPPINGER TR, 1991, J ANIM SCI, V69, P2808; COWDEN JM, 1989, BRIT MED J, V299, P771; DISIDERIO JV, 1985, INFECT IMMUN, V48, P658; FARID MF, 1979, P WORKSH CAM KART SU, P126; GIBBS HC, 1986, VET PARASITOL, V22, P57, DOI 10.1016-0304-4017(86)90007-5; HANLON AJ, 1995, APPL ANIM BEHAV SCI, V44, P57, DOI 10.1016-0168-1591(95)00575-D; KWANG J, 1995, FEMS MICROBIOL LETT, V130, P25; LAEMMLI UK, 1970, NATURE, V227, P680, DOI 10.1038-227680a0; MacFarlane W. V., 1964, HDB PHYSL 4, P509; MINTON JE, 1992, J ANIM SCI, V70, P1126; *MSTAT, 1991, SOFTW PROGR DES MAN; MULLER KH, 1991, J BACTERIOL, V173, P4765; Nagaraja KV, 1999, SALMONELLA ENTERICA SEROVAR ENTERITIDIS IN HUMANS AND ANIMALS: EPIDEMIOLOGY, PATHOGENESIS AND CONTROL, P397; NAKAMURA M, 1994, AVIAN DIS, V38, P717, DOI 10.2307-1592106; NRC, 1985, NUTR REQ SHEEP, P2; O'SULLIVAN B M, 1973, International Journal for Parasitology, V3, P521, DOI 10.1016-0020-7519(73)90049-0; Rhind SM, 1999, DOMEST ANIM ENDOCRIN, V16, P1, DOI 10.1016-S0739-7240(98)00051-4; RODRIGUE DC, 1990, EPIDEMIOL INFECT, V105, P21; Saeed A. M., 1999, SALMONELLA ENTERICA; SAHA AR, 1995, INT J IMMUNOPHARMACO, V17, P729, DOI 10.1016-0192-0561(95)00061-6; Sevi A, 2001, J ANIM SCI, V79, P1457; SMITH WD, 1983, J COMP PATHOL, V93, P295, DOI 10.1016-0021-9975(83)90016-6; TONEGAWA S, 1983, NATURE, V302, P575, DOI 10.1038-302575a0; TOWBIN H, 1979, P NATL ACAD SCI USA, V76, P4350, DOI 10.1073-pnas.76.9.4350; TURNER JC, 1979, COMP BIOCHEM PHYS A, V64, P167, DOI 10.1016-0300-9629(79)90446-8; VITETTA ES, 1991, ANNU REV IMMUNOL, V9, P193
Mostrar más [+] Menos [-]Palabras clave de AGROVOC
Información bibliográfica
Este registro bibliográfico ha sido proporcionado por American University of Beirut