Safety of cassia gum as a feed additive for dogs and cats based on a dossier submitted by Glycomer GmbH
2017
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) | Guido Rychen | Gabriele Aquilina | Giovanna Azimonti | Vasileios Bampidis | Maria de Lourdes Bastos | Georges Bories | Andrew Chesson | Pier Sandro Cocconcelli | Gerhard Flachowsky | Boris Kolar | Maryline Kouba | Secundino López Puente | Marta López‐Alonso | Alberto Mantovani | Baltasar Mayo | Fernando Ramos | Maria Saarela | Roberto Edoardo Villa | Robert John Wallace | Pieter Wester | Anne‐Katrine Lundebye | Carlo Nebbia | Derek Renshaw | Matteo Lorenzo Innocenti | Jürgen Gropp
Abstract The additive cassia gum consists mainly of high‐molecular weight polysaccharides composed primarily of a linear chain of 1,4‐β‐d‐mannopyranose units with 1,6‐linked α‐d‐galactopyranose units. In 2014, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) delivered an opinion on the safety and efficacy of cassia gum. The FEEDAP Panel concluded, based on positive findings observed in a bacterial reverse mutation test with a semirefined cassia gum (about 70 mg anthraquinones/kg) but not with purified semirefined cassia gum that meets the specification as a food additive (< 0.5 mg anthraquinones/kg), that only purified semirefined cassia gum that meets the specifications of cassia gum as a food additive can be considered safe for cats and dogs, at a maximum content of 1.5% cassia gum (15,000 mg/kg feed) in dry matter, corresponding to 1.32% (13,200 mg/kg feed) in a standardised complete feed with 12% water content. The FEEDAP Panel also concluded that cassia gum should be regarded as a skin and respiratory sensitiser and as a potential irritant to skin and eyes. Following this opinion, the European Commission gave the possibility to the applicant to submit complementary information on the safety for all animal species. No new data were submitted to address the potential of the additive to exert mutagenic effects, and therefore, the FEEDAP Panel is not in the position to modify the conclusions reached in the previous opinion.
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