Oxidative Stress on Buccal Mucosa Wound in Rats and Rule of Topical Application of Ethanolic Extracts of Mauli Banana ( Musa acuminata ) Stem
2015
Wenda Fitriati Noora | Novie Apriantia | Saldy Rizky Saputra | Balqis Afifah | Maharani Laillyza Apriasari | Eko Suhartono
The present study was undertaken to evaluate the effect of a topical application of ethanolic extracts of Mauli banana stem on oxidative status in buccal mucosa wounds of rats. The sets involved three groups, P0 was the negative control; P1 was treated with alocair topically; and P2 was treated with ethanolic extracts of Mauli banana stem topically, respectively, 24h after wound creation for 3 days. The oxidative stress status was evaluated by monitoring the SOD, CAT activity, MDA and CC levels. Ethanolic extracts of Mauli banana stem showed significantly increased in SOD activity, decreased in MDA levels, and no significant change both in CAT activity and CC levels compared to negative control. These results showed that The ethanolic extracts of Mauli banana stem might affect the oxidative stress status during wound healing process.
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