HIV-1 Transmission Dynamics Among Injecting Drug Users on a Risk Network Model
2010
Lou, Jie | Chen, Li
Using a "risk network" to describe the contact patterns(including needle sharing and sex behavior) of buddy relationships in injecting drug users(IDUs),a stochastic model is studied about the spreading of HIV-1 in IDUs.The basic reproduction number and the final size of the epidemic are obtained.In particular,the model has been applied to Xichang city.Through simulations,the effect of the injecting network size(and also the sex network size) in the spreading of HIV-1 in IDUs are studied.The model shows that 10% increasing of the final size of the epidemic need only one triple of needle sharing added for one IDU.The results give us very important hint: reduce the network sizes,especially the needle sharing network size should be a very important intervention measure to control the spread of HIV-1 in IDUs.
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