Exploring the interactions between polyunsaturated fatty acids and cadmium in rainbow trout liver cells: a genetic and proteomic study | Exploration des interactions entre acides gras polyinsaturés et cadmium dans des cellules de foie de truites arc-en-ciel : une étude génétique et protéomique
2018
Ferain, A. | Bonnineau, C. | Neefs, I. | de Saeyer, N. | Lemaire, Benjamin | Cornet, Vanessa | Larondelle, Yvan | de Schamphelaere, K.A.C. | Debier, C. | Rees, J.F. | Université Catholique de Louvain = Catholic University of Louvain (UCL) | RiverLy - Fonctionnement des hydrosystèmes ; Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA) | Universiteit Gent = Ghent University = Université de Gand (UGENT) | Université de Namur [Namur] (UNamur)
[Departement_IRSTEA]Eaux [TR1_IRSTEA]BELCA [ADD1_IRSTEA]Hydrosystèmes et risques naturels
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Mostrar más [+] Menos [-]Inglés. Polyunsaturated fatty acids (PUFAs) have key biological roles in fish cells. We recently showed that the phospholipid composition of rainbow trout liver cells (RTL-W1 cell line) modulates their tolerance to an acute cadmium (Cd) challenge. Here, we investigated (i) the extent to which PUFAs and Cd impact fatty acid homeostasis and metabolism in these cells and (ii) possible mechanisms by which specific PUFAs may confer cytoprotection against Cd. First, RTL-W1 cells were cultivated for one week in growth media spiked with 50 µmol L
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