THE EFFECT OF HCG, 17 Β-ESTRADIOL AND HYDROCORTISONE ON BLOOD CHOLESTEROL,
2009
Wasfi Dhahir Abd Ali Al -Mahmod
The aim of this study is to investigate the effect of human chorionic gonadotophic (HCG), 17β-estradiol and hydrocortisone on some blood parameters and body weight in female rabbits. Twenty local rabbits were subdivided randomly and equally into four groups . The1st group used as control . The 2nd group was injected daily (30 IU /kg B.W) HCG intramuscularly . The 3rd group was injected subcutaneously daily with 0.1 mg /kg B.W s/c 17 β-estradiol and the 4th group was injected daily 0.1 mg /kg B.W intramuscularly hydrocortisone. After five weeks blood serum was tested for total Cholesterol, HDL(height density lipo-protein), LDL (low density lipo- protein),TG (triglycerides), total protein and pH. Body weight was taken dialy from first day . The results showed that the administration of HCG raised high significantly LDL(p>0.01) while total Cholesterol , TG, glucose failed to reach the significant level, .However HCG significantly lowered HDL (p>0.01) Total protein and body weight were decreased with no change in blood pH compared with the control group. The treatment with 17β-estradiol decreased the level of cholesterol , , TG and lowered significantly HDL(p 0.05 >and increased significantly LDL (p > ( 0.05. Glucose and total protein were increased with no significant effect on body weight and pH compared with the control group. While hydrocortisone increased ,HDL ,TG ,LDL and glucose and decreased cholesterol and total protein level moreover body weight and pH did n,t effected
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