Dataset: miRNA profile in colostrum exosomes of dairy ewes (F0) supplemented with methionine during the early life

Methionine supplementation during the suckling period of ewe lambs (F0) might program persistent changes on DNA methylation, thus modifying miRNA profile of colostrum exosomes during the lactation period when these animals are adults. Identifying these changes is important because may drive some effects on the offspring (F1) under natural rearing conditions. The results of the present study revealed changes in miRNA profile of colostrum exosomes as a consequence of methionine supplementation during the suckling period of ewe lambs (F0).

This work was funded by Ministerio de Ciencia e Innovación (PID2021-126489OB-I00, MCIN/AEI/10.13039/501100011033, “FEDER, Una manera de hacer Europa”); ACRONYM: NUPROVI Alba Martín gratefully acknowledges receipt of a pre-doctoral grant (PRE2019-089288) from Ministerio de Ciencia e Innovación (MCIN/AEI/10.13039/501100011033, “El FSE invierte en tu futuro”); CSIC is acknowledged for supporting Open Access publication.

1M_L001_R1_001.fastq.gz (F0-MET) 1M_L001_R2_001.fastq.gz (F0-MET) 8C_L001_R1_001.fastq.gz (F0-CTRL) 8C_L001_R2_001.fastq.gz (F0-CTRL) 19C_L001_R1_001.fastq.gz (F0-CTRL) 19C_L001_R2_001.fastq.gz (F0-CTRL) 28M_L001_R1_001.fastq.gz (F0-MET) 28M_L001_R2_001.fastq.gz (F0-MET) 31M_L001_R1_001.fastq.gz (F0-MET) 31M_L001_R2_001.fastq.gz (F0-MET) 35C_L001_R1_001.fastq.gz (F0-CTRL) 35C_L001_R2_001.fastq.gz (F0-CTRL)

Peer reviewed