EFFECT OF KAOLIN ON BIOCHEMICAL PARAMETERS AGAINST AEROMONAS HYDROPHILA IN CYPRINUS CARPIO
2024
Muthana N. Al-Ghazaly | A. J. Al-Rudainy
The present study aimed to evaluate the role of kaolin on hematological and biochemical profiles of common carp, Cyprinus carpio infected with Aeromonas hydrophila, A total of 180 of common carp were collected 40 g ; 60 fish were used to determine the median lethal dose LD50 of A. hydrophila, )LD50 was 1.57 × 106 CFU/ml) for 15 days. 120 fish were randomly distributed into six treatment groups (10 fish/treatment in duplicate) as follows: C- served as control negative group (without infection and treatment); C+ act as control positive group (infected with A. hydrophila but not treatment with Kaolin); T1, T2, T3 and T4 were intraperitoneally (IP) injected with A, hydrophila (at dose of 0.1 ml) and then treated with Kaolin at concentrations of 2, 4, 6 and 8 g/L respectively. In hematological indices, the experimental groups of carp (C+, T1, T2, T3 and T4) showed a significant (P<0.01) decrease in the number of erythrocytes, Hb content and PCV% compared to C- group. While, WBC numbers showed a significant (P<0.01) increase in all experimental carp groups relative to the C- group. As far as biochemical profile are concerned, the experimental groups of carp (C+, T2, T3 and T4) reported a significant (P<0.05) increase in total protein compared to C- group. In Globulin, Groups (T2, T3 and T4) showed a significant (P<0.01) increase compared to C- group. In conclusion, the treatment of common carp with Kaolin particularly at concentration of 8 g/L (T4) reduced the effect of A. hydrophila.
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