Adipokines are a group of proteins that are synthesized from adipose tissue. Omentin is a type of adipokine which is detected in human serum and it is evaluated as a secreted factor from adipose tissue, placenta and ovarium. The knowledge about the effect of omentin on reproduction is limited. In the presented study, investigation of omentin effect on in vitro uterine contractions was evaluated. The uteruses of the rats which were collected from 20 virgin female rats, were isolated and suspended in the isolated organ bath. The experimental protocols were carried out in 3 groups. The effect of omentin on spontaneous uterine contractions in protocol 1, induced by oxytocin (2.5 mIU/mL) in protocol 2, and induced uterine contractions with PGF2α (10-6 M) in protocol 3 was tested. The effect of omentin on isolated uterine tissues was tested with the administration of 10, 100 and 300 ng/mL omentin. 300 µL of distilled water was applied to the control of each group. In this study, 10, 100 and 300 ng/mL of omentin applied for 10 minutes did not have an effect on uterine contractility in all study groups (p>0.05). As a result, further studies with higher doses and longer incubation times are recommended.

In the present multidisciplinary study, the researchers on a field trial performed a Social Network approach and a group of 9 calves (3 males/6 females) aged 10 to 16 weeks. A 24 hours digital camera was used for location registration (X-Y position) and interactions on each calf, both individually and collectively. Based on the simple methodology nearest neighbor matrix positive and negative associations were analyzed. The field study lasted 4 weeks and the maximum interaction day was chosen, when individual calf activity was high. To those of 9 calves solely no 2 was infected with giardiasis on the first week, whereas calves with no:2, 7, and 8 were also infected on the second week. No: 4 and 6 were also infected with a total of 5 calves on the third week. This was followed by the final 6 calves in total infected. During the observation period, both by investigators and camera records, infected calf 2 was in close contact with no: 8 (at morning observation) and a slight degree of contact with no: 3 and 4 which were detected with giardiasis on the third and fourt weeks, respectively. Due to close contact with no: 8, infection was determined on the second week, earlier than others (except no: 7). Calves with no: 1 and 5 were never infected nor determined by PCR, fecal smear, or rapid diagnostic test kits throughout the study. In conclusion, the present authors suggested that social networking might be an important predisposing factor for giardiasis infection among calves.

The aim of this study was to determine the prevalence of Dirofilaria immitis (D. immitis) in dogs in the Ardahan region. The study material consisted of 100 Akbaş crossbred dogs (53 females and 47 males) between the ages of 3-7 in Ardahan region. An immunochromatographic analysis test kit was used to determine seroprevalence. The presence of antigen against D. immitis was determined as 12% (12/100). When the dogs with antigens against D. immitis were evaluated according to their age, it was determined that the highest positivity was in 4 years old (15%) (P˃0.05). Antigen presence against D. immitis was detected in 10.6% of male dogs and 13.2% of female dogs (P˃0.05). According to the data obtained from this study, it was concluded that D. immitis was seen in dogs in the Ardahan region and that protection and control measures should be taken for the eradication of this disease due to reasons such as global warming, wildlife and lack of education.

Radial and ulnar fractures are common in small animals. Especially toy and miniature breed dogs are at high risk of incidence. Although there are plenty of studies on the treatment of radius and ulna fractures in small animals, studies related to the radius and ulna fractures in toy and miniature breed dogs are limited. The objective of this study was to report the diagnostic information and treatment outcome of radial and ulnar fracture treatment in toy and miniature breed dogs. Radius and ulna fractured 22 toy and miniature breed dogs were included in the study. Clinical findings, radiographic images, treatment applications, prognosis and outcomes were evaluated. As a treatment method, external coaptation in 5 extremities and surgical reduction and osteosynthesis in 17 extremities were performed. Out of 5 dogs who underwent external coaptation, 4 had good outcome and 1 had malunion. Out of 17 patients which underwent surgical treatment, 13 had a good outcome, 2 had nonunion, 1 had surgical site infection, and 1 had malunion and implant failure. As a result, original data on the etiology, diagnosis, treatment, prognosis evaluations, and surgical outcomes of radius and ulna fractures of toy and miniature breed dogs were presented. External coaptation considered could be successful in closed and undislocated radius and ulna fractures of toy and miniature breed dogs. However, the surgical approach and osteosynthesis performing are considered essential in dislocated, comminuted, complicated fractures, or open fractures. Further prospective studies are needed to compare specific surgical treatment methods.

Present research was conducted at the University of Aydin Adnan Menderes, Faculty of Veterinary. In a total of 10 cats with pruritic dermatoses were allocated, classified [Feline atopic skin syndrome (FaSs)] and adapted to the retrospective case controlled study on the basis of Polycheck in vitro Allergy Test, clinical signs, dermatoscopic and cytological examination. No prior drug prescription, nor immunosuppressive treatment were evident, which was an inclusion criteria. Complete blood count, serum biochemistry, and endocrine panels were all deemed available on days 0 and 21 for all cats involved. The Feline Dermatitis Extent and Severity Index (FeDESI) and a 10 cm visual analog scale (VAS) were deemed available as relevant prognostic parameters. A three strain invoving soil-based probiotic used via rectal route significantly decreased FEDESI and VAS pruritus scores after 10 days of rectal use. Pre-treament day 0 FEDESI scores (median ± SD) (106.3 ± 41.38), were significantly higher than scores on day 10 (15.3 ± 10.53) switching the severity of the disease to mild status in all cases. Furthermore, day 0 VAS pruritus scores were 7.4 ± 1.78 (mean ± SD) (prior to treatment), whereas owner VAS pruritus score was decreased to 1.3 ± 1.06 (mean ± SD) significantly (p=0.005). It should not be unwise to draw preliminary conclusion that 3 chained soil-based Bacillus probiotic was capable of short term cure for FaSs. Bacillus probiotics with safety usage should be added to therapeutical armamentarium of FaSs.

In this study, it is aimed to investigate the effects of intracameral mydriatic combinations on the pupil dilation (PD), intraocular pressure (IOP), heart rate (HR) and mean arterial pressure (MAP). In this study 35 animals were divided into 5 groups. The first group (MSic) was phenylephrine hydrochloride (Mydfrin) and cyclopentolate hydrochloride (Sikloplejin),  the second group (TLic) was tropicamide (Tropamid) and 2% lidocaine,  the third group (BSS) was balanced salt solution. Cats were anesthetized, and all solutions were injected intracamerally. The fourth group (MSt) was phenylephrine hydrochloride (Mydfdrin) and cyclopentolate hydrochloride (Sikloplejin) and the fifth group (TLt) tropicamide (Tropamid) and 2% lidocaine were given by topically. During this research, the fastest onset of the mydriasis was numerically formed by first group. All intracameral groups were seen having longer duration of mydriasis compared to topical groups. Intraocular pressure decreased after anterior camera paracentesis in all intracameral procedures. In our study, time dependent changes of heart rate were found to be statistically significant in all groups. Our research observed that first and second group successfully created enough mydriasis (>10mm). In terms of pupil diameter, it has been proven that first and second group are usable alternatives administration, and no side effects on intraocular pressure, heart rate or mean arterial pressure.

This study was aimed to determine whether the reference values affected by different times of the day and season in Saanen Goats. One hundred twenty-two goats were included to this study and, tear secretion (TS) and intraocular pressure (IOP) were measured in three different time periods as morning, noon and evening on the same day in each seasonal group. Temperature and humidity values were recorded during all measurements. There was no difference between the right and left eyes in terms of IOP and TS (p>0.05). While mean TS value was significantly increased in the winter group (12.23±0.28 mm/min) compared with the spring (9.9±0.18 mm/min) and summer (9.14±0.19 mm/min) groups (p<0.001), mean IOP was significantly decreased in the winter group (14.05±0.28 mmHg) compared with the spring (17.64±0.36 mmHg) and summer (17.32±0.43 mmHg) groups (p<0.001). While mean TS value was significantly increased at noon (10.08±0.28 mm/min) compared with morning (10.99±0.24 mm/min) (p<0.001), mean IOP was significantly decreased in the morning (14.95±0.31 mmHg) compared to the afternoon (17.63±0.35 mmHg) and evening (16.54±0.42 mmHg) (p<0.001). In conclusion, TS and IOP values in Saanen goats are affected by different times of the day and season, and it will contribute to the literature by determining the values that can be taken as reference for these different daytime and seasonal profile of the IOP and TS in Saanen Goat.

In this review, the use of some feed additives in the diets of ruminant animals is discussed. Brief information about the anatomy of the digestive system of ruminants and the metabolism of some nutrients in these animals are presented. In addition, summary information about some feed additives used in animal nutrition is given. Particularly detailed information about pre/probiotics among feed additives is presented, and the effects of S. cerevisiae, known as yeast, are discussed. In ruminant animals, unlike the monogastrics, feed additives, especially pre-and probiotics, are utilized to affect fermentation in the rumen. In addition, it is seen that it is used to increase immunity in pre-ruminants. However, it is obvious that more studies are needed on these issues.

Artificial joint prostheses are preferred as a good treatment alternative for joints that are difficult or impossible to treat. With the advancement of technological possibilities, the joints that need to be locked or amputated are saved by total joint prostheses. Although there is relatively more information about total hip joint replacements, there is not enough information and experience about total knee replacements. Active use of total knee replacement in veterinary surgery will improve the standard of living of many animals. The aim of this review is to provide information about total knee replacement, which is not yet widely used, and to consider it among treatment alternatives.

Propolis is a resinous natural product produced by honey bees by mixing collected buds and exudates of plants with bee wax. Bees use propolis to protect themselves against wind and rain by using it to construct and repair hives. Propolis has a wide range of biological effects as it is a mixture of natural substances, and it is widely used for its anti-inflammatory, anti-oxidant, immunomodulatory, and anti-cancer effects. Propolis has been used in traditional medicine since time immemorial. Research studies on the anti-tumor effects of propolis extracts and components such as flavonoids, phenolic acids, and their esters demonstrate their potential to be used in the development of new anti-tumor agents. Propolis shows an anti-carcinogenic effect against cancers of the brain, head and neck, skin, breast, liver, pancreas, kidney, bladder, prostate, colon, and blood. In-vivo and in-vitro studies have shown that propolis has cytotoxic, anti-genotoxic or anti-mutagenic, anti-proliferative, anti-angiogenic, anti-metastatic, and proapoptotic properties. Its main mechanisms in cancer treatment can be explained as prevention of metastasis, arrest of the cell cycle, induction of apoptosis and alleviation of harmful side effects caused by chemotherapy. The beneficial effects of natural products on human health have been reported in studies to prevent tumor formation and/or suppress the growth of tumors into cancer. In this review, detailed information about the properties, biological effects, and anti-cancer effects of propolis was given by reviewing current literatures.