Anthelmintics are used traditionally as an integral part of helminthic control strategies for grazing livestock to prevent production losses from parasitic infections. The continuous and indiscriminate use of the same anthelmintics over years together as the sole means of control are now failing due to the emergence of resistance strains of helminths. Resistance to the commonly used anthelmintics in gastrointestinal nematodes of sheep has become an increasingly wide spread problem throughout the world. The present study was aimed to determine the resistance against albendazole, fenbendazole, levamisole and closantel in gastrointestinal nematodes of sheep. Fifty five naturally infected Madras Red lambs of 6 - 12 months of age were selected and distributed randomly into five treatment groups of eleven animals each. Four groups were treated orally with albendazole (5mg/kg), fenbendazole (7mg/kg), levamisole (7.5m/kg) and closantel (10 mg/kg) respectively, while the fifth group served as untreated control.  Faecal samples were collected per rectum of each lamb just prior to treatment (pre treatment) and then on days 7, 14, 21 and 28 after treatment. The anthelmintic resistance was evaluated by in vivo faecal egg count reduction test (FECRT), post treatment larval culture and in vitro egg hatch assay. In the faecal egg count reduction test, albendazole reduced the faecal egg count by 86.50 per cent, 84.81 per cent, 85.28 per cent and 84.47 per cent respectively for four weeks after treatment. Faecal egg count reduction using fenbendazole was 92.64, 93.04, 90.80 and 90.06 per cent respectively for four weeks after treatment.  The per cent efficacy for levamisole and closantel was more than 95 per cent. The post treatment larval culture contained only Haemonchus contortus. In the in vitro egg hatch assay, the ED 50 value for benzimidazole was 0.299 µg thiabenazole/ml and levamisole showed an ED 50 value of 0.283 µg /ml.

Hydatidosis, caused by the larval stage of the dog tapeworm, Echinococcus granulosus is considered to be an important condition in herbivores such as cattle, buffaloes, sheep and goats. Due to its presence in the food animals meant for meat purpose, the disease is considered to be of economic and public health significance owing to the impact it produces on the meat industry by condemnation of the affected organs. Food animals such as sheep, goats get infected by accidental ingestion of contaminated feed and water with the eggs of the tapeworm. Development of the cysts in the intermediate host such as sheep and goats occurs in the lungs, liver and other visceral organs. The disease remains asymptomatic in most cases in spite of the presence of the hydatid cysts for a long period. A study was undertaken to find out the incidence of the hydatid cysts in sheep and goats in the Corporation slaughter house by examination of the carcasses of the slaughtered sheep and goats. By the study, an overall incidence of 6.5% in sheep and 5.8% in goats were observed with the sheep harbouring more number of fertile hydatid cysts which plays a major role in dissemination of infection to dogs.

In - vivo evaluation of  the  efficacy of test anti - coccidial efficacy of salinomycin and amprolium carried out in two different trials in 228 commercial chicken revealed 100% efficacy against mixed eimeria sp on comparative evaluation with standed in feed anti - coccidials.  There was marked reduction in the oocyst output with increased body weight gain and improved feed conversation efficiency in the experimental study.

The genus Capripoxvirus (CaPV) comprises three members namely, sheep pox virus (SPPV), goat pox virus (GTPV) and lumpy skin disease virus (LSDV) affecting sheep, goats and cattle, respectively. Capripoxvirus infections produce similar symptoms in sheep and goats, and the three viruses cannot be distinguished serologically. The Capri pox virus disease is an economically important notifiable disease of cattle, sheep and goats (OIE, 2018). This article reviews about the current scenario of Capri pox disease and the better opportunities for prevention and control of disease. Recent outbreaks of the disease have caused the major economic loss in most of the countries including India.

The present study was aimed to assess the seroprevalence of brucellosis in sheep of Cauvery Delta region by collecting serum samples from apparently healthy sheep and sheep with the history of abortion. Serum samples from a total of about 123 animals including 64 from apparently healthy animals, 54 from animals with previous history of abortion and 5 from aborted animals were subjected to serological tests like Rose Bengal Plate Test (RBPT), Standard Plate Agglutination Test (SPAT) and indirect Enzyme Linked Immuno-sorbent Assay (i-ELISA). Molecular identification was carried out with the aborted materials from 5 animals with Bcsp31 gene. The prevalence rate of Brucellosis was 26.01 %, 22.76 % and 41.46 % by RBPT, SPAT and i-ELISA respectively. Among the 5 aborted animals, two were found to be positive for brucellosis with all the four diagnostic tests. Among the three serological tests, the highest seroprevalence of 41.46 % was observed when i-ELISA was used. However, RBPT was considered to be cost effective and easy to test. Hence, from this study it can be concluded that periodical screening of animals with cost effective serological tests for diseases like brucellosis, which is of economic and public health significance is mandatory to prevent the disease outbreak and economic loss to thefarmers.

Leptospirosis is a zoonotic disease caused by pathogenic species of Leptospira interrogans. Dogs can act as maintenance host for some serovars and transmit to other animals and humans through direct and/or indirect contact with urine or contaminated water and soil. A study was conducted to identify the presence of Leptospira and assessment of seroprevalence in apparently healthy dogs in Cauvery delta region (Thanjavur, Thiruvarur and Nagapattinam districts) of Tamil Nadu. Serum (n=50) and urine (n=50) samples were collected randomly from 50 dogs with history of non vaccination to leptospirosis. Dark field microscopic (DFM) examination revealed the presence of Leptospira in 12.0 per cent of serum and 24.0 per cent of urine samples. Serological screening was done by microscopic agglutination test (MAT) using a battery of 12 Leptospira serovars (representing the serogroups of Australis, Autumnalis, Ballum, Canicola, Grippotyphosa, Hardjo, Hebdomadis, Icterohaemorrhagiae, Javanica, Pomona, Pyrogenes and Tarassovi), which revealed 56.0 per cent seropositivity to either one or several serovars, which was Icterohaemorrhagiae (46.4 per cent), Grippotyphosa (32.1 per cent), Australis (32.1 per cent), Canicola (25.0 per cent) and Autumnalis (17.9 per cent) with highly significant difference (p<0.05) in seropositivity between serovars. The predominant serovar detected in dogs in this study was Icterohaemorrhagiae followed by Grippotyphosa. It is concluded that presence of leptospirosis in dogs in Cauvery delta regions of Tamil Nadu poses the risk of transmission to animals and humans and dogs can be used as sentinel animals for identification of leptospirosis.

A nine year old non-descript male dog was presented to Madras Veterinary College Teaching Hospital with a history of anorexia, weakness, and clinical signs of respiratory distress and pyrexia. TFAST (thoracic-focused assessment with sonography for trauma) of the lung was performed to rule out pleural effusion. Upon confirmation of pleural effusion, thoracocentesis was performed and sample was collected to identify the cause. The pleural effusion was confirmed as haemothorax and cytology of the sample wasconfirmed as mesothelioma. 

An experiment was conducted to study the effect of dietary supplementation of calcium, carnitine, zinc and their combinations for 5 weeks in eighty adult crossbred cocks which were divided into eight treatment groups each consisting of ten cocks. Cocks were fed with treatment diets. The treatment groups consisted of control (T1), control + calcium 2 per cent (T2), control + carnitine 250 mg/kg (T3), control + zinc 100 mg/kg (T4), control + calcium 2 per cent + carnitine 250 mg/kg (T5), control + calcium 2 per cent + zinc 100 mg/kg (T6), control + carnitine 250 mg/kg + zinc 100 mg/kg (T7) and control + calcium 2 per cent + carnitine 250 mg/kg + zinc 100 mg/kg (T8). Semen volume revealed no significant difference between treatment groups during five weeks period. Overall sperm motility was significant (P<0.01) between treatment groups except between T4 and T5 groups. Overall sperm concentration was significantly (P<0.01) higher in all treatment groups compared to control. Inclusion of calcium, carnitine, zinc and their combinations had significantly (P<0.01) reduced the overall dead and abnormal of sperms when compared to the control group. The results revealed that inclusion of 2 per cent calcium, 250 mg/kg of carnitine, 100 mg/ kg of zinc and their combinations in feed improved the sperm motility and concentration in cross-bred cocks. 

An investigation among fifty each tribal and non-tribal dairy farmers in four dairy dominated development blocks of Cachar district of Assam revealed that, among tribal and non-tribal farmers attitude towards dairy farming, economic motivation and source of motivation for dairy communication were found to have favourable scores with positive and significant correlation with communication behaviour. Regression analysis revealed that source of motivation for dairy communication crucially influenced communication behaviour of dairy farmers. Further, there louid significant difference between the tribal and non-tribal dairy farmers indicating sensitive strategies for dairy development in the area involving the veterinarians. 

The present study was carried out to evaluate the effect of curcumin on lipid peroxidation and antioxidant levels in DMBA (7, 12 Diemthyl Benanthracene) induced mammary carcinogenesis in rats. Twenty four Sprague-Dawley rats were equally distributed to control, DMBA, Tamoxifen (Standard drug) and curcumin groups. DMBA group showed significant (P<0.05) increase in lipid peroxidation and antioxidants superoxide dismutase (SOD) and catalase (CAT) levels besides reduced glutathione (GSH). Whereas, curcumin and Tamoxifen treated groups did not show any significant difference in lipid peroxidation and antioxidant status when compared to the control. Selective growth advantage of tumour cells was evident in the DMBA group and curcumin was able to prevent lipid peroxidation.