In the conditions of the Republic of Belarus there was analyzed the efficiency of bactericidal action of tartaric acid aerosol for air sanitation of poultry buildings and increasing of broiler chickens viability. The bactericidal action was analyzed by the example of Staphylococcus aureus, Eschericia coli and Proteus vulgaris. In course of study there were analyzed biochemical indexes of blood and blood serum, lymphoid tubercle in proper mucous plate of trachea of broiler chickens after 6-time treatment with tartaric acid and Ekotsid C preparation. Research results showed that the analysed preparations did not render negative influence on metabolic indexes of broiler chickens and increase poultry viability. Application of tartaric acid did not cause pathomorphologic changes in tissues and organs of birds, stimulated the active proliferation of leucocytes in immune system organs (thymus gland; spleen; and lymphoid tissue).

In the conditions of the Republic of Belarus there was studied the pathology and biology of cattle capillariasis. Capillariosis invasion rendered a substantial invasion on blood morphological composition which was revealed in lowering of erythrocytes and hematoglobulin, as well as in increasing of leukocytes quantity. There was noted the lowering of the natural resistance and immune reactivity. There were stated substantial deviations in protein metabolism which was expressed in lowering of total protein, quantity of albumins, changing of albumin and globulin coefficient, increasing of globulins. In the conditions of blood biochemical analysis of infesrated animals there was stated a disorder of vitamin and mineral metabolism; increasing of alanine aminotransferase and aspartate aminotransferase enzymes activity. Development of Capillaria bovis was realized in a direct line. In the natural habitat development of Capillaria bovis eggs varied from two up to three months.

In the conditions of the Republic of Belarus annually in 25-50% of total number cattle there was stated ketosis (milk fever); as a result, from each cow in cattle breeding farms receive less milk per lactation on 10-15%, as well as there is a lowering of fat and protein (and biological value) content in milk. In course of the study there was analyzed the influence of mineral and energy supplement Felutsen K-1-2 for the preventive treatment of ketosis of highly productive cows. Research results showed that application of the analyzed additive rendered the positive influence on morphological and biochemical blood indexes. In particular, there was an increasing of hemoglobin level, content of total protein, albumins, magnesium, calcium, and phosphorous. It also rendered positive influence on lipid exchange. In course of the study it was marked, that the prophylactic efficacy of mineral and energy supplement Felutsen K-1-2 in the experimental groups was 100%, and the control one – 80%.

In the conditions of the Republic of Belarus there were analyzed the peculiar features of morphology of bursa of Fabricius of turkeys broad-breasted white turkeys at the stage of postnatal ontogenesis. Research results showed that postnatal ontogenesis of bursa of Fabricius of turkeys developed irregularly with preservation of organ up to 220 days. At turkeys in 300-day old age the organ preserved only in 45% of bird units. Form, colour and consistency of bursa of Fabricius depended on bird age. The absolute weight of the organ increased up to 220 days. The relative weight was maximum at 20-day old age. The sexual peculiar features of the organ morphology were insignificant; they revealed after the beginning of sexual maturity and expressed by some difference in weight and linear dimensions.

Influence of inorganic and organic salts of lithium on activity of amplifiers and concentration of metabolites in plasma of chicken blood in the process of vaccination against infectious bursal disease was studied in the conditions of the Republic of Belarus. After administration of lithium of citrate, sulfate and succinate there were noted the metabolic disorders. Research results testified that a dry live-viral vaccine on the basis of a strain KMIEhV-61 did not render essential influence on biochemical indicators of blood plasma. At the same time, immunization of chickens against application of salts of lithium (carbonate, sulphate, citrate, succinate) caused to authentic decrease in activity of alanine aminotransferase that testified to function oppression of hepatocytes. Application of lithium of citrate, sulfate and succinate made it possible to considerably increase the concentration of uric acid that was connected, apparently, with infringement of secretory function of kidneys. Metabolic disorders were observed in various terms of research - at 3, 7 and 14 days after vaccine administration. | Изучено влияние неорганических и органических солей лития на активность индикаторных ферментов и концентрацию метаболитов в плазме крови цыплят при вакцинации против инфекционной бурсальной болезни (ИББ). Выявлены метаболические нарушения при использовании лития цитрата, сульфата и сукцината. Полученные результаты исследований свидетельствуют о том, что сухая живая вирус-вакцина из штамма КМИЭВ-61 не оказывает существенного влияния на биохимические показатели плазмы крови. В то же время иммунизация цыплят на фоне применения солей лития (карбонат, сульфат, цитрат, сукцинат) приводит к достоверному снижению активности АлТ, что свидетельствует об угнетении функции гепатоцитов. Применение лития цитрата, сульфата и сукцината способствует также достоверному повышению концентрации мочевой кислоты, что связано, по-видимому, с нарушением выделительной функции почек. Метаболические нарушения наблюдаются в различные сроки исследований - на 3, 7 и 14 дни после введения вакцины.

Research of a pancreas of geese in course of different age-specific periods was realized in the conditions of the Republic of Belarus. Ecological features of water fowl inhabitance, prevalence of phytogenous forages in a diet of led in first two life decades to rapid growth of body weight and pancreas which was capable to adapt an organism to new conditions of existence. The subsequent growth and differentiating processes in a pancreas of geese showed direct correlative dependence on the basic physiological states of their organism (plumage, a moult, puberty, egg production efficiency). By the beginning of egg production (6 months) the basic structural components of secretory parts of gland of geese reached a rather developed condition, but their full morphological and functional maturity occurred by 2-year-old age, possibly, because of a long reproductive period of life. | Проведено исследование поджелудочной железы у гусей в разные возрастные периоды. Экологические особенности среды обитания водоплавающих птиц, преобладание в рационе кормов растительного происхождения приводят в первые две декады жизни к бурному росту массы тела животных и поджелудочной железы, способной адаптировать организм к новым условиям существования. Последующие ростовые и дифференцировочные процессы в поджелудочной железе гусей проявляют прямую коррелятивную зависимость от основных физиологических состояний их организма (оперение, линька, половое созревание, яйценосная продуктивность). К началу яйценоскости (6 месяцев) основные структурные компоненты секреторных отделов железы гусей достигают достаточно развитого состояния, но их полная морфофункциональная зрелость наступает к 2-летнему возрасту животных, вероятно, из-за продолжительного репродуктивного периода жизни.

Research on determination of changes of morphological and biochemical blood indexes of sheep with fasciolosis after application of the drug Klozantsid (menizol 20%, produced in the Republic of Belarus) was carried out. The research realized in the conditions of the Scientific and Research Institute of Applied Veterinary Medicine and Biotechnology of the Vitebsk State Academy of Veterinary Medicine. In course of the experiment there were used sheep of Romanovskaya breed at the age from 1,5 till 5 years which were spontaneously infected with fasciola. The experimental animals were administrated with the examined antihelminthic preparation. It was found out that after administration of the preparation there was stated the restoration of a level of erythrocytes, haemoglobin, leukocytes, enzymes, proteins and other blood indexes. Klozantsid did not render toxic influence on studied animals. | Проведены исследования по выяснению изменений морфологических и биохимических показателей крови у овец с фасциолёзной инвазией при применении препарата Клозанцид. Исследования проводили в условиях клиники и лаборатории кафедры паразитологии и инвазионных болезней, лаборатории кафедры клинической диагностики, научно-исследовательского института прикладной ветеринарной медицины и биотехнологии учреждения образования «Витебская ордена «Знак Почёта» государственная академия ветеринарной медицины». Объектом исследования являлись овцы романовской породы в возрасте от 1,5 до 5 лет, спонтанно зараженные фасциолами, которым применяли испытуемый препарат, обладающий антигельминтными свойствами. При этом выяснено, что после введения препарата происходит восстановление уровня эритроцитов, гемоглобина, лейкоцитов, ферментов, белков и других показателей. Клозанцид не оказывал токсического влияния на организм животного.

Morphological and biological characteristic of isospora and eimeria was realized in the conditions of the Republic of Belarus on the basis of carried out measurements and experimental infection minks (Mustela). Research results showed, that in Belarus at mink breeding farm holdings there were determined four species of eimeria and isospores, one of which I. eversmanni - is registered by researchers from the Vitebsk State Academy of Agriculture in the Republic for the first time. The most widespread species is Е. vison (57,03%) was found out in all analyzed 24 fur breeding farms. Species composition of eimeria and isospores did not depend on a sex and typical coat pattern of minks, as well as on a geographical location area of an analyzed farm. Some distinctions in species composition of the intestinal protozoa were observed at minks of different age. Of all analyzed species the most pathogenic proved to be Е. vison and I. laidlawi which in case of infectioning caused animal mortality. | Дана морфологическая и биологическая характеристика изоспор и эймерий на основании проведенной микрометрии и экспериментального заражения норок. Таким образом, по результатам проведенных нами исследований следует отметить, что в Республике Беларусь у норок, разводимых в хозяйствах, установлено четыре вида эймерий и изоспор, один из которых - I. eversmanni - зарегистрирован нами в республике впервые. Самым распространенным видом является Е. vison (57,03%), обнаруженный во всех обследованных нами 24-х зверохозяйствах. Видовой состав эймерий и изоспор не зависит от пола и типовой окраски норок, а также от географического месторасположения хозяйства. Некоторые различия в видовом составе кишечных простейших наблюдались у норок разного возраста. Из отмеченных видов наиболее патогенными являются Е. vison и I. laidlawi, вызывающие при заражении падеж зверей.

In the conditions of the Republic of Belarus there were presented the results of a veterinary and sanitary assessment and bacteriological investigation of sheep slaughter products, which showed meat serviceability for consumption after application of Triclafen suspension. Application Triclafen suspension did not render negative influence on an organism of animals. It was proved by organoleptic and laboratory research of meat of slaughter animals of experimental and control groups. The meat obtained from healthy sheep which were administrated the suspension in accordance with microbiological indicators proved to be of good quality and corresponded to the established norms (Sanitary regulations and standards 11 - 63 Republic of Belarus 98): it had the general bacterial content within admissible limits and did not contain agents of anthropozoonosts, alimentary toxicosis and toxinfections and it can be sold without any restrictions.

In the conditions of the Republic of Belarus there was realized a complex of studies of quality swine slaughter products against the background of combine applications of the albuminous-vitamin-mineral additive Immovit and an extract of hill-growing saltwort for the preventive maintenance and treatment of a toxic dystrophy of liver. Research results showed the analysed preparations did not render negative influence on quality and safety of produced meat products. Against the background of application of the albuminous-vitamin-mineral additive Immovit in combination with an extract of hill-growing saltwort there was stated the improvement of swine slaughter product quality. In products from the animals which were administrated with a complex of examined preparations there was stated an optimized moisture content, the increasing of a relative biological value of a product (101,3-103,8%), and according to the indexes of bacterial safety the experimental pork considerably surpassed the meat indexes from animals of control groups. At the same time, in slaughter animal products of control groups there were revealed coliform bacillus bacteria.