Safe meat production is an important aspect to avoid human health hazards. The use of probiotics in poultry is an important tool to produce safe meat among several established biotechnological approaches. In this experiment, we studied the effects of probiotics for producing safe Japanese quail meat. 150 Japanese quail chicks were reared for a period of six weeks using various doses of probiotics (0, 0.5, 1, 1.5, and 2g per litre of water). The chicks were randomly distributed into five treatment groups with three replications each. The number of birds in each replication was 10. After rearing six weeks, significantly high body weight was found at probiotic concentrations of 1, 1.5, and 2g per litre of water. The feed intake in various treatments did not differ significantly, but comparatively better feed conversion ratios were observed at probiotic treatments. Water quality was not significantly differed as a result of addition of probiotics to the water. The reason for this better growth performance is probably due to the multiple benefits of probiotics in poultry. Probiotics could have maintained gut health with better nutrient utilization and availability that might have been led to higher body weight gain in the quail. In future experiments, challenging the birds with diseases or comparing probiotics with antibiotic growth promoters is required to ensure the efficiency of probiotics.

This study investigated the effects of various guar gum edible coating formulations, incorporating different proportions of waste leek powder and sunflower oil, on weight loss, color parameters (L*, a*, b* values, and ΔE), texture, and shrinkage of Agaricus bisporus mushrooms during a 7-day storage period. The goal was to assess the potential impact of these coatings on preserving the mushrooms’ quality over time. The results showed that the coatings had a significant effect on reducing weight loss compared to uncoated samples. The lowest weight loss was observed in the 0.5% leek powder and without sunflower oil, while the highest was in 2.5% leek powder and 0.1% sunflower oil. Shrinkage was also positively affected by the coatings, with 1.5% leek powder and without sunflower oil showing the most promising results. The L* values of the coated samples declined slightly, indicating better color preservation, while the a* values exhibited stable redness/greenness. On the other hand, b* values increased, indicating an increase in yellowness during storage. The ΔE values were lower for the coated samples, suggesting less color deviation compared to uncoated ones. Overall, the study indicates that these edible coatings have the potential to maintain the quality of mushrooms during storage, leading to better preservation and extended shelf life.

Erzincan Tulum Cheese (ETC) holds a significant place among the most popular cheeses in Türkiye. It has been awarded Protected Geographical Indication status, which restricts the allowable milk species, its production area, and specific sheep breed used in its production. Mineral content and antioxidant activity of ETC were aimed to be predicted using conventional FT-NIR and a portable FT-MIR spectrometer combined with partial least square regression (PLSR) and machine learning algorithms based on conditional entropy. Seventy ETC samples were analyzed for their mineral (Al, Ca, Cr, Cu, Fe, K, Mg, Mn, Na, and P) content using ICP-MS. The samples' antioxidant activity was measured using the DPPH•+ scavenging activity method. PLSR combined with FT-NIR spectral data correlated with antioxidant activity (r=0.89) and minerals (as low as r=0.83) except for Cr and Fe. FT-MIR data provided a good correlation for minerals (as low as r=0.82) except for Cr and Mn and a moderate correlation with antioxidant activity (r=0.64). Information theory was applied to select wavenumbers used in machine learning algorithms, and better results were obtained compared to PLSR. Overall, FT-NIR and FT-MIR spectroscopy provided rapid (~ 1 min), non-destructive, sensitive, and reliable output for mineral and antioxidant activity predictions in commercial cheese samples.

Toxoplasma gondii and Neospora caninum are obligate intracellular protozoan parasites that can affect different warm-blooded species worldwide. In this study, it was aimed to detect T. gondii and N. caninum using PCR method in brain tissues of aborted sheep fetuses. Brain specimens were collected from 50 Morkaraman sheep fetuses that had undergone abortion at various stages of pregnancy, within the lambing seasons of 2023 in Muş. Approximately 1 cm³ of brain tissue from the right cerebral hemisphere was excised and subsequently frozen at -20°C for DNA extraction. DNA extraction and PCR amplification were then performed. As a result of this study, 11 (22%) of 50 brain tissues were positive. All brain samples examined in this study were negative for Neospora caninum. Based on the results of this study, it is possible to say that T. gondii is an important abortion agent in sheep in this region. Although N. caninum was not detected in this study, larger scale studies are recommended. Moreover, this study provides important information to breeders and veterinarians in the field in the evaluation and management of abortion.

The aim of this study is to cover the design-implementation processes of the museum interiors of the museum building in Selçuk University campus, which consists of foyer, temporary and permanent exhibition areas that can realize the aims and functions of the museum in accordance with the culture of the institution to which it is affiliated. Two types of materials were used within the scope of the study. The first type of material is theoretical and visual information based publications, thesis studies, lecture notes, architectural and interior design printed publications and internet resources. The information scanned and analyzed was handled from general to specific. The second material is the analysis of the Selçuk University Museum building located in Selçuk University Alaeddin Keykubat Campus by the authors with the on-site identification stages, interviews with the relevant people, the requirements of the museum foyer, temporary, permanent exhibition areas and existing interior photographs. The method followed in the study is observation and detection. As a result of the researches and observations made by utilizing publications, thesis studies, course notes, architectural and interior architectural printed publications and internet resources on the subject, an identification study was carried out in the existing museum building. As a result of the research, it was stated that the museums within the university campus have an important place in terms of establishing a bond between the public and the university, apart from the educational areas affiliated to the institution.  Apart from education and training structures, from a different perspective, it was mentioned that they are common multi-purpose areas and the positive aspects they add to the institution to which they are affiliated. The interior revisions made in the determined areas of the museum building, the project design process and the implementation phases were mentioned.

Supercritical-CO2 extraction, Soxhlet extraction, and ultrasound-assisted extraction methods were conducted in this study to recover valuable components, specifically phenolic antioxidant compounds, from orange peels. Basic operating parameters such as temperature and pressure, which affect the extraction efficiency of phenolic substances in orange peel with supercritical-CO2, were designed using the central composite design methodology. In the Soxhlet and ultrasound-assisted extraction methods, 2-hour extraction processes were carried out using ethanol at different concentrations (50%, 80% and 100%) as a solvent. Yield comparison was made by performing total phenolic content, antioxidant activity and total flavonoid content analyses in the extracts. The total phenolic content (TPC) in the extracts was determined to be 5034 mg GAE/L for supercritical-CO2 extraction at 61.5°C and 20 MPa. In comparison, Soxhlet extraction yielded a TPC of 1728 mg GAE/L, while the ultrasound-assisted extraction method resulted in a TPC of 4056 mg GAE/L. It was determined that the optimum operating parameters of supercritical-CO2 extraction were 60°C and 26.4 MPa in case all the responses were maximized. The best phenolic recovery was obtained at 100% ethanol in Soxhlet extraction and 80% ethanol in ultrasound-assisted extraction. Although supercritical-CO2 extraction is an environmentally friendly application, the recovery rate of valuable components from raw materials is lower than in Soxhlet extraction and ultrasound-assisted extraction. However, since the volume of the extracts obtained from the supercritical-CO2 extraction is small, the ratio of phenolic compounds is higher.

Animal wastes are not stored correctly and are used haphazardly without control in agricultural lands. As a result, it causes many irreparable environmental pollution, especially water pollution. These wastes, which are described as diffuse pollution, cause pollution of both underground and surface water resources directly or indirectly and even make them unusable. In this research, waste generation as a result of animal breeding in Karaman province, its districts, neighborhoods and villages and the effects of animal wastes on environmental pollution were evaluated with distributed pollutant load calculations. In the study, the number of 1019277 ovine and 81368 bovine in Karaman in 2022 was used. The total nitrogen (TN) produced annually by the animals has been calculated as 1,723.23 tons/year, and the total phosphorus (TP) amount is determined as 124.23 tons/year. Additionally, for large ruminant animals, the annual total amount of dry manure is 130,305.77 tons, and for small ruminant animals, it is 41,984.27 tons. To prevent environmental pollution, these wastes should be stored in closed areas in compliance with standards, and processes such as composting, drying, and biogas production should be applied. By doing so, not only can environmental pollution be mitigated but also economic value can be obtained. The proper management and utilization of these wastes have high economic potential and can contribute to sustainable development, supporting the country’s economy. In addition, this study is a source for researchers working in the field in calculating the pollution load of animal wastes and is thought to be a guide for decision makers and practitioners.

The maize weevil (Sitophilus zeamais Motschulsky) causes significant quantitative and qualitative losses during storage. To identify resistant varieties of maize against this pest, an experiment was conducted in a Completely Randomized Design (CRD) with 11 varieties in free and no-choice conditions. The study measured weight loss, mean bored grain, debris, and weevil numbers at 30, 60, and 90 days. The findings showed that BG13Y-POP, Manakamana-7, and RML-19/RML-6 were the most resistant varieties, with weight loss percentages of 1.99%, 1.47%, and 1.74%, respectively, and final weevil numbers of 104, 72, and 73. Ganesh-2 and ZM-401 were the most susceptible varieties, with weight losses of 7.34% and 6.05%, respectively. The maximum debris weight was found in RML-761/RL-105 (1.98 g), while the minimum was found in Manakamana-7 (0.26 g). The highest number of bored grains was observed in Ganesh-2 (81), while the lowest number was observed in Rampur-4 (51). Similarly, ZM-401 (158) and Ganesh-2 (165) exhibited the highest weevil population, while the lowest count was found in Rampur-4 (72). Overall, using resistant varieties, such as Manakamana-7, BG13Y-POP, and RML-19/RML-6, can be an effective approach for reducing post-harvest losses from weevil infestation.

Bu çalışmada, geleneksel yöntemle üretilmiş zeytin ve elma sirke biyofilmlerindeki bakteriyel popülasyon farklılıkları; türlerinin izolasyonu, bakteriyel 16S rRNA geninin V3 bölgesinin PZR (Polimer Zincir Reaksiyonu) amplifikasyonu ve ardından DGJE (Denatüre Edici Gradyan Jel Elektroforezi) ile PZR DGJE (Polimeraz Zincir Reaksiyonu Denatüre Edici Gradyan Jel Elektroforez) yöntemiyle belirlenerek, DNA dizi analizleriyle tanımlanmıştır. Elde edilen diziler, BLAST (Basic Local Alignment Search Tool = Temel Bölgesel Hizalama Arama Aracı) analizi ile hizalanmıştır. Filogenetik analiz için MEGA X (Molecular Evolutionary Genetics Analysis, X) programı kullanılmıştır. Zeytin sirkesi örneklerinde Komogataeibacter rhaeticus baskın tür olarak, elma sirke örneklerinde ise sirke bakterisi olarak bilinen Komogataeibacter xylinus (Gluconacetobacter) baskın tür olarak tespit edilmiştir. Geleneksel üretim yöntemiyle üretilen sirkelerdeki bakteriyel türlerin tanımlanması ve izolasyonu ile bu bakteriler kültür olarak depolanmıştır.

Sıçanlarda paklitaksel (PTX) kaynaklı akciğer hasarına karşı misoprostol’ün (MP) koruyucu etkilerinin incelendiği bu çalışmada, yirmi bir adet dişi Sprague-Dawley cinsi sıçan kullanıldı. Bu hayvanlardan rastgele bir seçimle Kontrol, PTX ve PTX + MP olmak üzere 3 grup (n=7) oluşturuldu. Kontrol grubuna 1 mL %0,9 NaCl intraperitoneal (i.p.) ve 1 mL %0,9 NaCl oral yolla 6 gün boyunca verildi. PTX ve PTX + MP gruplarına çalışmanın 0., 2., 4. ve 6. günlerinde her sıçana 2 mg/kg PTX i.p. olarak verildi. PTX + MP grubuna ayrıca 6 gün süreyle 0,2 mg/kg/gün MP oral olarak verildi. Doku numuneleri sıçanlardan anestezi altında alındıktan sonra bu numunelerde biyokimyasal ve histopatolojik analizler yapıldı. Yapılan analizlerde PTX grubu sıçanlarda akciğer dokusundaki süperoksit dismutaz (SOD) ve katalaz (CAT) aktiviteleri ile glutatyon (GSH) düzeyinin azaldığı, malondialdehit (MDA) düzeyinin ise yükseldiği belirlendi. Yapılan histopatolojik incelemelerde ise, PTX grubu sıçanlarda alveol yapısında düzensizlik ve kalınlaşma, perivasküler ödem ve perivasküler alanda inflamatuar hücre infiltrasyonu gibi histopatolojik değişikliklerin şekillendiği tespit edildi. PTX + MP grubunda ise, PTX grubunda tespit edilen patolojik değişikliklerin büyük oranda önlendiği görüldü. Elde edilen bu sonuçlar; PTX’in neden olduğu akciğer hasarının önlenmesinde MP’nin etkili olduğunu göstermekte olup, kanser tedavisinde bu iki ilacın birlikte kullanılmasının faydalı olacağını düşündürmektedir.