Diffusion of penicillin from treated to untreated quarters of buffaloes
1986
Singh, R.S. | Kaul, A. (National Dairy Research Inst., Karnal (India). Div. of Dairy Microbiology)
The release of penicillin into milk after intramammary infusion of aqueous suspensions of the drug in different doses, namely, 100,000; 500,000, and 1,000,000 I.U. was studied. Excretion of penicillin in milk was found upto 48 hr, when the doses administered were 100,000 and 500,000 I.U. on increasing the dose to 1,000,000 I.O. the persistence of penicillin in milk was found upto 60hr. The study further revealed the presence of penicillin in untreated quarters upon intramammary infusion of aqueous suspension of penicillin in one quarter. Based on present investigation, milk from treated udder should be with held for 72hr. The diffusion of the drug from the treated to untreated quarters further suggested to consider udder as a single unit instead of four quarters. Hence, milk should be discarded from the whole udder instead of from the treated quarters only
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