Muscle and liver cellular growth as affected by the stage of development and faba bean intake in rats [Vicia faba]
1986
Barcina, Y. | Martinez, J.A. | Cenarruzabeitta, E. | Larralde, J. (Univ. of Navarra, (Spain). Dept. of Animal Physiology and Nutrition)
Young and adult male wistar rats were fed ad libitum on diets containing casein or faba beans as protein source. After 10 days liver and gastrocnemius muscles were removed and analyzed for protein, DNA, and RNA contents. There was a significant weight difference between animals fed the different protein sources, while differences in liver protein between treatments were not significant. There were marked decreases in DNA contents of both tissues. Legume-fed rats had higher liver RNA: protein ratios, which were significantly different in older rats. The impairment of growth observed in rats fed the legume diet was attributed to reduced muscle protein synthesis
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