Escherichia coli mastitis in periparturient cows: an overview of ten years of research on the role of neutrophil leukocytes in local and systemic reactions
1996
Dosogne, H. | Burvenich, C. (Gent Univ., Merelbeke (Belgium). Faculteit Diergeneeskunde. Vakgroep Fysiologie, Biochemie en Biometrie)
Mastitis is determined by environmental factors, cow related factors and pathogens. During the last ten years many insights have been gathered that lead to the suggestion that neutrophil leukocytes play an important role during acute coliform mastitis in dairy cows around the time of parturition. Upon the invasion of micro-organisms in the mammary gland, peripheral blood leukocytes migrate into the udder in large numbers. Opsonization, phagocytosis and intracellular killing are meant to eliminate the hazardous mastitis pathogens. In this review, the qualitative and quantitative aspects of these cell functions before and during experimentally induced infections are discussed along with the local and the systemic reactions that are involved in this process.
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