Efficacy study of Newcastle disease virus (NDV4) V4 strain vaccine in chicken in Nepal
1996
Bohara, K.B. | Mishra, U. (Animal Health Research Division, Tripureswor, Kathmandu (Nepal))
Efficacy of the oral NDV4HR strain vaccine against Nepalese velogenic field strain of NDV (ND-NP1/95) was investigated in experiment I. Oral vaccination with drinking water provided 80 percent protection against the challenge with ND-NP1/95, a very virulent local strain of NDV. The result of feed based vaccination were rather inconclusive. Experiment II was carried out to simulate the natural field storage conditions and their impact upon protection offered by V4HR strain vaccine. The vaccine held at 28 degree centigrade and 37 degree centigrade for an extended period of 6 days did not offer protection against challenge with velogenic ND-NP1/95 whereas vaccine held at 4 degree centigrade offered protection against same challenge.
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