Case report of an autosomal dominant polycystic kidney disease in a Persian cat | La maladie des reins polykystiques chez le chat: cas clinique
2000
Vanloubbeeck, Y. | Desmecht, D. | Cassart, D. | Coignoul, F. (Universite de Liege, Sart Tilman (Belgium). Faculte de medecine veterinaire. service de pathologie generale)
Polycystic kidney disease in Persian cats closely resembles the autosomal polycystic kidney disease in human beings. Both diseases are inherited as autosomal dominant traits. They are characterized by the development and enlargment of cysts in the renal cortex and medulla resulting in progressive renomegaly. Finally, both diseases usually are accompanied by renal failure late in life. The marked clinical and morphological similarities of APKD in Persian cats and the human disease, as well as the autosomal dominant inheritance pattern, suggest that the feline condition is a potential model for the study of APKD in humans.
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