Effects of cimetidine on broiler fattening and on stress-induced gizzard erosion in chicken
1999
Grabarevic,Z. | Dzaja,P. | Peric,J. | Serman,V. | BiDin,I. | Mazija,H. | Mas,N. | Mikulec,Z. | Culjak,K. | Simec,Z. | Njari,B.
Three-day-old chicks (30/group) were treated intragastrically with 0.5 ml saline or with cimetidine at 5 mg/kg body weight, subjected to stress by immersion in tap water for a few seconds and then killed 1, 2 or 3 h later.The mean length of gizzard erosion (GE) was decreased in cimetidine-treated chicks compared with controls.In a second experiment, day-old chicks (16/group) were untreated or given cimetidine at 10 mg/kg feed for 42 days.Treated chicks had reduced liveweight (1835.1 g), carcass weight (1474.6 g) and increased feed consumption (2115 g/kg weight gain) compared with untreated chicks (1898.5 g, 1574.2 g and 1797 g, respectively).It is concluded that while stress-induced GE of chicks can be medicated pharmacologically, long-term application of the same substance impairs growth performance.
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