Postnatal development of Harderian gland in Mongolian gerbil

Oh, S.H.; Park, J.Y.; Seong, J.K. . Department of Laboratory Animal Medicine, Medical Research Center, College of Medicine; Yoon, Y.S.; Lee, J.S. . Department of Veterinary Histology and Embryology, College of Veterinary Medicine; Kim, D.J. . Toxicological Research Institute; Nam, S.Y. . Department of Veterinary Anatomy

Postnatal development of Harderian gland in Mongolian gerbil

1999

Oh, S.H. | Park, J.Y. | Seong, J.K. (Yonsei University, Seoul (Korea Republic). Department of Laboratory Animal Medicine, Medical Research Center, College of Medicine) | Yoon, Y.S. | Lee, J.S. (Seoul National University, Suwon (Korea Republic). Department of Veterinary Histology and Embryology, College of Veterinary Medicine) | Kim, D.J. (Korea Food & Drug Administration, Seoul(Korea Republic). Toxicological Research Institute) | Nam, S.Y. (Tokyo University, Tokyo (Korea Republic). Department of Veterinary Anatomy)

This investigation was carried out to study morphological and chronological aspects of the development of the Harderian gland in the Mongolian gerbil(Meriones unguiculatus). Male and female Mongolian gerbils were sacrificed on days 1, 3, 5, 10, 30 and 60 after birth and their Harderian glands were processed for light microscopic observation. The result obtained were summarized as follows; 1. In 1-day-old Mongolian gerbil, Harderian gland was well distinguished from other tissue structures. It was composed of several immature tubules, and these tubules were separated each other by undifferentiated mesenchymal connective tissues. 2. In 3-day and 5-day-old Mongolian gerbils, the arrangement of tubules in the gland was more condensed than that of 1-day-old Mongolian gerbil. The excretory ducts started to appear in the connective tissues located between lobes. 3. In-10-day-old Mongolian gerbil, small lipid vacuoles began to be found in the cytoplasm of the secretory cells of the Harderian gland. There were some mucus-secreting cells within the epithelium of the excretory duct found in the interlobar connective tissues. 4. In 30-day-old Mongolian gerbil, there was markdely increased number of the tubules in the glands. The epithelial cells of the tubules were typically columnar in shape. Most of the columnar epithelial cells contained many small lipid vacuoles, although a few cells contained large lipid vacuoles. 5. In 60-day-old Mongolian gerbil, the Harderian gland exhibited the typical structural characteristicsl of the adult gland. The mature glandular structrues were more distinct than those of 30-day-old animals.

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