Air pollution, inflammation and cerebrovascular disease - A hypothesis
2001
Sjogren, B.
This paper discusses the possible association between air pollution and cerebrovascular disease. In the mid 1990s a theory was launched that both urban and occupational air pollution may induce alveolar inflammation, with release of mediators such as fibrinogen capable of increasing blood coagulability and cause cardiovascular disaese. This hypothesis is expanded and some evidence linking occupational and urban air pollution to the occurence of cerebrovascular disease are presented. Results from some studies of occupations (farmers, miners, glassworkers) and chemical exposures (metals, polycyclic aromatic hydrocarbons) illustrate this hypothesis. It should, however, be tested by case-referent studies in geographical areas where occupational dust exposure is common.
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