Method of Using Hydrolysis to Increase Paclitaxel Yield from Plant Cell Culture
2000
Kim Jin-Hyun | Kang In-Seon Samyang Genex Biotech Research Institute, Taejon (Korea Republic)
This work is a method that uses a hydrolysis for increasing yield of paclitaxel in plant cell cultures. The best pH is 3.0 to obtain a maximum yield at fixed reaction temperature and time. At pH 3.0, reaction temperature 80 degrees and reaction time 8 hr give the highest yield which is three times of control. This is very simple and efficient method to increase paclitaxel yield in plant cell cultures.
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