Effects of immunization with porcine zona pellucida and oocytes upon reproductive function in the bitch
2000
Mircu, C. (Faculty of Veterinary Medicine, Timisoara (Romania)) | Cernescu, H. | Ghise, Gh. | Ardelean, V. | Bonca, Gh. | Igna, V.
In the present work, we have investigated the effect of administration of porcine zona pellucida alone (ZPp), or together with its oocyte (OV+ZPp), on reproductive function in the bitch. Bitch immunization consisted of 6 consecutive injections at 3 week intervals and each dose contained 500 ZPp (alone or together with their oocytes). In the first two bitches immunized with ZPp, high titres of antibodies suppressed fertilization, for 7 months, but exerted no effect upon sexual cyclicity. Bitches that were immunized with OV+ZPp, also developed high titres of antibodies, suppressive for fertilization and lasting for a longer period (10 months). However, these animals had reproductive disorders. Both immunocontraceptive methods were 100% effective.
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