Porcine pleuropneumonia: the first evaluation of field efficacy of a subunit vaccine in Croatia
2002
Habrun, B. | Bilic, V. | Cvetnic, Z. | Humski, A. | Benic, M. (Croatian Veterinary Institute, Zagreb (Croatia))
A vaccine for porcine pleuropneumonia caused by Actinobacillus pleuropneumoniae was studied in Croatia on a farm infected by agent serotypes 2 and 9. Vaccination with a commercial subunit vaccine was initiated in the second half of 1998 due to the immense economic damage caused on the farm by this disease. All pre-fattening and fattening pigs kept on the farm during the first three months of 1999 were allocated in two groups: vaccinated and control. In the control and vaccinated group, 226 and 35 animals (5.78 % and 0.96 %), respectively, died from pleuropneumonia. The vaccine efficacy was 83.5 %. Examination of the randomly selected lungs on the slaughter line revealed significant reduction in the lesions specific for the chronic form of pleuropneumonia in the vaccinated group (vaccine efficacy 78.6 %). The tested vaccine significantly decreased the death rate and pulmonary lesions due to A. pleuropneumoniae.
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