The silencing of (trans) genes - a mechanism of virus resistance in plants. I. Two biological phenomena - one mechanism
2002
Kiraly, L.
One of the interesting surprises in plant biotechnology in the past decade was the occasional observation that transgene constructs designed to supplement the expression of endogenous genes may display the effect of co-suppressing themselves and the endogenous genes; furthermore, virus-derived transgenes in plants can be poorly expressed and yet provide excellent virus resistance. In the light of recent research these two phenomena (co-suppression and RNA-mediated virus resistance) appear to result from post-transcriptional gene silencing (PTGS), an RNA-dependent defence mechanism occuring in plants, animals and fungi.
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