Efficacy of various drugs against blood protozoa in Kundhi buffaloes

502 buffaloes were examined randomly and data was recorded on designed performa. The data collected showed 39.21 percent (197 animals) infection of different blood protozoa (Anaplasma, Babesia and Theileria). The prevalence of Anaplasmosis, Babesiosis, Theileriosis, Babesiosis + Anaplasmosis, anaplasmosis Theileriosis, Babesiosis Theileriosis and Anaplasmosis + Babesiosis + Theileriosis was 20.11, 5.97, 2.39, 6.77,1.19, 1.39 and 1.39 percent respectively. Present study showed that. light intensity infection was more prevalent in all infections like, Anaplasina, Babesia, Theileria, Anaplasma + Babesia, At it Anaplasma + Theileria, Babesia + Theileria and Anaplasma + Babesia + Theileria (66.66, 63.33, 58.82, 66.66, 71.42 and 71.42 percent respectively), followed by moderate (22.77, 36.66, 16.66, 41.17, 33.33, 28.57 and 28.57 percent respectively) while, heavy infection 9.90 percent was only observed in Anaplasma and severe infection prevailed as 0.99 and 16.66 percent in Anaplasma and Theileria respectively. Four groups were made viz. A, B, C and D. Group A was subdivided into A-I (5 animals of pure Anaplasmosis) and A-II (5 animals of mixed infections of Anaplasmosis and Babesiosis). Group A-1 was treated with lmizol at the (lose rate of 3 mg/kg body weight with single therapeutic close. Out of 5 animals complete recovery was recorded in one animal, moderate recovery in two animals while, two animals showed no response to Imizol, although both were completely recovered with two doses of 4 mg/kg body weight. Group A-II was treated with lmizol if the dose rate of .3 mg / kg body weight with single therapeutic dose out of 5 animals, complete recovery was recorded in one animal, moderate recovery in three animals while, one animal showed no response to lmizol. Group B with babesiosis was treated with Diminazene at the close rate of 3. 5 mg/kg body weight with single therapeutic close. Out of ten complete recoveries was recorded in 6 animals, moderate recovery in two animal whereas, two animals showed no response to Diminazene. Group C with Theileriosis was treated with Butalex at the close rate of 2.5 mg/kg body weight with single therapeutic lose. Out of eight, complete recovery was recorded in 4 animals, two animals showed no response to Butalex while, two animals with severe infection flied after 24 hrs. Response to drug did not appear to directly relate to the age of animals. In infected control group (Group-B) four animals of Anaplasmosis were observed for time related changes. Three animals showed 110 changes while, in animal infection was increased front light to moderate. Out of two animals of mixed infection of Anaplasmosis and Babesiosis one infection was increased one animal from heavy to severe While; other animal remained in same status. Both the animals of Babesiosis showed change in infection. Out of two animals kept for Theileriosis, in one infection was increased from light to moderate while, in other infection remained same.