Humoral immunity in puppies of immune bitches vaccinated with an attenuated and inactivated vaccine against parvoviral infection in dogs
2002
Bacic, D. | Obrenovic, S. | Valcic, M. | Trailovic, D.R. | Dobric, Dj. (Fakultet veterinarske medicine, Beograd (Serbia and Montenegro))
In order to examine the humoral immune response to a vaccine against canine parvovirus in puppies of immune bitches, vaccinated during gravidity, and experiment was performed on a total of 56 puppies from 10 litters, which were vaccinated three times, on the 7th, 11th, and 17th weeks of life. One group of puppies was vaccinated with an attenuated vaccine, while another was vaccinated with an inactivated vaccine. The titer of maternal antibodies and the vaccine - induced titer of specific antibodies were examined using the IHA test. The titer of maternal antibodies in puppies before the first vaccination ranged from 20 to 1:80. Following vaccination, we established an expected increase in the titer of specific antibodies, over 1:160, without more significant differences between the two types of vaccines.
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