Antioxidative activity of resveratrol and its derivatives isolated from seeds of Paeonia lactiflora
2002
"Kim, H.J. (Catholic Univ. of Taegu-Hyosung, Kyungbuk (Korea R.)) | Chang, E.J. | Cho, S.H. | Chung, S.K. | Park, H.D. | Choi, S.W. "
"Seven stilbenes, a new cis-e-viniferin and the six known stilbenes, trans-resveratrol, trans-resveratrol-4f-O-v-D-glucopyranoside, trans-e-viniferin, gnetin H, and suffruticosol A and B, were isolated and identified from seeds of Paeonia lactiflora. The antioxidative activity of these stilbene derivatives was evaluated against the 2-deoxyribose degradation and rat liver microsomal lipid peroxidation induced by the hydroxyl radical generated via a Fenton-type reaction. Among these stilbenes, trans-e-viniferin and gnetin H significantly inhibited 2-deoxyribose degradation and lipid peroxidation in rat liver microsomes. In addition, cis-e-viniferin, and suffruticosol A and B also exhibited moderate antioxidative activity. These results suggest that resveratrol dimers and trimers, together with resveratrol from seeds of Paeonia lactiflora may be useful as potential sources of natural antioxidants. "
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