The investigation on the estrogenic activities in foodstuffs
2004
Nagahora, S. (Hokaaido Inst. of Environmental Sciences, Sapporo (Japan)) | Aga, H. | Akutagawa, T. | Numabe, A. | Murata, K. | Sakata, K.
Endocrine Disrupting Chemicals (EDCs), so called environmental hormones, are suspected to induce the abnormality to human and wildlife by disturbing the endocrine function, especially sex hormone system. Estrogenic active chemicals were suspected to feminize the male organisms. Meanwhile, the foods containing estrogenic substances are regarded as valuable to keep feminine and to reduce post menopausal diseases. The possibility of causing some effects for the ecosystem is considered when these foods are disposed, and discharged into the water environment. We investigated the estrogenic activity in foodstuffs, juices and drinks by Yeast Two-Hybrid system. Only the supernatant fluid of miso-soup showed estrogenicity. The source of estrogenicity was considered daizein and genistein. But assuming that estrogenicity caused by only genistein, the content of genistein was too low compared with literature. This showed that almost of estrogenic substances was contained in the precipitation part.
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