Effects of Dietary Factors on Lymphocyte DNA Damage in Smoking Elderly People in Korea
Kang, M.H.(Hannam University, Daejeon, Republic of Korea)E-mail:[email protected] | Lee, J.H.(Chonan College of Foreign Studies, Chonan, Republic of Korea)
The spontaneous frequency of genetic damage and the possible relationship of this damage to dietary and nutritional variables were investigated in peripheral blood lymphocytes from 45 elderly people using sister chromatid exchange (SCE). The relationship of dietary and nutritional factors on SCE was assessed by different degrees of smoking status such as smokers (n=14), ex-smokers (n=16) and non-smokers (n=15). Significant relationship of the SCE frequency to nutrient intake of the combined subjects (n=45) was found. When cigarette smoking status was taken into account, there were negative linear relationships between SCE and fat, phosphorus or vitamin A intakes of the non-smokers as well as SCE and the dietary quality scores. There was a positive linear relationship between SCE and food frequency of meat and fish among the smokers.
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