Water-Immersion-Restraint Stress model in Mongolian gerbil for comparison of pathogenicity of Helicobacter pylori strains
Lee, J.U.;Kim, O.J.(Seoul National University, Seoul, Republic of Korea)E-mail:kimoj@snu.ac.kr
Helicobacter pylori (H. pylori)-infection is an important pathogen of stomach cancer after chronic gastritis and ulceration in the stomach and duodenum. However, the virulences of H. pylori strains have not been well-defined between clinical isolates. This study was designed to establish water-immersion-restraint stress (WIRS) model in mongolian gerbil for comparison of pathogenicity of H. pylori strains. To determine an optimal duration time for WIRS model in gerbil, 5-week-old Mongolian gerbils were divided into different groups by WIRS duration time.
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