Effect of Artemisia anomala S. Moore on Antioxidant Activity and Melanogenesis
2005
Cho, Y.H. (Hanbul Cosmetics Corporation, Seoul, Republic of Korea), E-mail: [email protected] | Lee, B.C. (Hanbul Cosmetics Corporation, Seoul, Republic of Korea) | Kim, J.H. (Hanbul Cosmetics Corporation, Seoul, Republic of Korea) | Kim, J.H. (Hanbul Cosmetics Corporation, Seoul, Republic of Korea) | Pyo, H.B. (Hanbul Cosmetics Corporation, Seoul, Republic of Korea) | Zhang, Yong He (Peking University, Beijing, China) | Park, H.D. (Daegu University, Gyeongsan, Republic of Korea)
In mammalian melanocytes, melanin synthesis is controlled by tyrosinase, the key enzyme in the pigment synthesis. In this study, to develop a new whitening agent, we have investigated the antioxidant activity and the inhibitory effect of Artemisia anomala extract on tyrosinase activity and melanogenesis in the B16/F1 melanoma cells. The inhibition ratio of tyrosinase activity of butanol faction form A. anomala was higher than that of arbutin (97.5±0.5% at the concentration of 2 mg/ml).
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