Nutritional myodegeneration as a cause of dysphagia in adult horses: three case reports
2007
Ludvikova, E.,Veterinarni a Farmaceuticka Univ., Brno (Czech Republic). Klinika Chorob Koni | Jahn, P.,Veterinarni a Farmaceuticka Univ., Brno (Czech Republic). Klinika Chorob Koni | Lukas, Z.,Masarykova Univ., Brno (Czech Republic). Ustav Patologie
Three cases of nutritional myodegeneration caused by selenium deficiency in adult horses are described. Difficulty in eating and drinking was a common clinical sign in all horses. Blood biochemistry revealed a marked elevation of muscle enzymes and low glutathione peroxidase activity or low Se concentration in whole blood in all cases. The treatment with sodium selenite and vitamin E was instituted in all horses. Two of them were euthanized because of continuing muscle injuries, one patient was cured. The postmortem examination of euthanized horses revealed pale muscles that were distributed with bilateral symmetry on hind and thoracic limbs, diaphragm, tongue, masticatory and intercostal muscles and the myocardium. Histopathology revealed the areas of degeneration and necrosis. Large groups of regenerating fibres and pronounced lymphoplasmocytic reaction among the groups of intact fibres were also present. The clinical outcome of the disease is probably influenced by timely diagnosis and treatment.
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