Over-Expression of Chlamydia Psittaci MOMP in Escherichia Coli and its Purification
2006
Ha, J.S. (Kyonggi University, Suwon, Republic of Korea) | Lee, D.B. (Kyonggi University, Suwon, Republic of Korea) | Han, S.H. (Kyonggi University, Suwon, Republic of Korea) | Lim, Y.K. (Cheju National University, Jeju, Republic of Korea) | Yoon, B.S. (Kyonggi University, Suwon, Republic of Korea), E-mail: bsyoon@kyonggi.ac.kr
Generally known psittacosis or ornithosis is a disease of birds caused by the bacterium Chlamydia psittaci. Humans are accidential hosts and are most commonly infected from avian sources. It raises hepatitis or neurosis. As major outer membrane protein (MOMP) of Chlamydia psittai has been known to play a role in the avoidance of host immune defenses, research on developing a Chlamydia vaccine has focused on the MOMP. In this study, the gene encoding the major outer membrane protein (MOMP) of the Chlamydia psittaci strain 6BC was cloned and expressed in Escherichia coli Strain M-15.
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