Effect of vitamin E supplementation on immunity against Newcastle disease virus in T-2 toxin challenged chickens
2008
Weber, M.,Szent Istvan Univ., Goedoelloe (Hungary). Dept. of Nutrition | Fodor, J.,Kaposvar Univ. (Hungary). Research Group of Animal Breeding and Hygiene of the Hungarian Academy of Science | Balogh, K.,Szent Istvan Univ., Goedoelloe (Hungary). Dept. of Nutrition | Wagner, L.,Veszprem Univ., Keszthely (Hungary). Inst. of Animal Science | Erdelyi, M.,Szent Istvan Univ., Goedoelloe (Hungary). Dept. of Nutrition | Mezes, M.,Szent Istvan Univ., Goedoelloe (Hungary). Dept. of Nutrition
The effect of T-2 toxin contaminated feed (2.35 mg/kg) and/or vitamin E supplementation in drinking water (10.5 mg/animal/day) for 14 days on the haemagglutination inhibition titres against Newcastle disease virus was investigated in repeatedly vaccinated (on 23 days of age) broiler chickens. The animals were divided into four groups as follows: (1) control; (2) treated with vitamin E; (3) fed a T-2 toxin contaminated feed; (4) fed a T-2 toxin contaminated diet and treated with vitamin E. Blood samples were taken on days 7 and 14 of the experiment for determination of sera titres and vitamin E content, liver samples were also taken for vitamin E determination. Haemagglutination titres increased in comparison with control animals as an effect of vitamin E supplementation and also a low dose of T-2 toxin. The combination of both treatments showed some synergistic effect. The utilization of vitamin E decreased when feeding the contaminated diet, particularly in the liver.
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