The present and future conditions of drugs promoting castrointestinal function in small animals
2006
Sato, K.(Yamaguchi Univ. (Japan). Faculty of Agriculture)
In the small animal therapy, the disorder of digestive organs is one of the most common diseases. The disorder is caused by the infection of microorganisms, virus or parasites, and also poisonings, intestinal tumor, stress-induced disease, allergic disease, and so forth. In some cases the disease is so serious that the animals need immediate attention and care. In other cases they need only resting cure. The diversity of the disorder is not only due to the etiology but also the complexity of digestive organs. The digestive system is composed of many types of organs, such as esophagus, stomach, intestine, liver, gallbladder, and pancreas. All of these organs have different types of structure and function, and accordingly the disorder of digestive organs is diverse. The secretion of many types of digestive juice and the permeability of mucosa for digesting food, and absorbing the digestive food are regulated in both small intestine and large intestine. The contraction and relaxation of intestinal smooth muscle, called peristalsis, regulate the motility of these organs to move the food through the tract, and to eliminate the wastes left over. The motility of these intestines is important to regulate the circumstances in intestinal tract and the enterobacterium. Because of these reasons, it is important to know the gastro-intestinal disorder and to propose the therapeutic strategy. In this article the author will review the mechanism of intestinal motility, the motility disorder of intestine, and introduce the relationship of inflammatory bowel disease with intestinal motility disorder.
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