Efficacy and safety of Japanese rabies vaccine (inactivated) in cats according to the import-export quarantine regulation for dogs and other animals
2007
Ezoe, S.(Chemo-Sero-Therapeutic Research Inst., Kikuchi, Kumamoto (Japan)) | Saijo, K. | Takikawa, N. | Yasuda, H. | Yamanaka, M.
The efficacy and safety of the Japanese rabies vaccine (inactivated) for veterinary use was investigated in cats inoculated twice as required by the Import-Export Quarantine Regulation for Dogs and Other Animals. There were no clinical symptoms or local reactions following the vaccinations of cats injected twice with one dose and three times with one dose, once with two doses and twice with ten doses. After two injections with a month's interval between them, the cats had a virus neutralization titer (VNT) of 11,026 one month after the last injection and a high VNT of 5,347 one year after the last injection. With two injections at an interval of about one year, the VNT increased to 1,318 at one month after the first injection, and maintained a high VNT of 796 at the time of the second injection. At one month after the last injection, the VNT had increased to 21,081. Based on the above results, the two-vaccination method of cats with Japanese rabies vaccine as provided by the Quarantine Regulations was considered safe and effective.
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