Anti-Oxidation of Cultured Cordyceps militaris Growing on Silkworm Pupa
2006
Gong, Cheng-Liang (Suzhou University, Suzhou, P. R. China), E-mail: chlgong@tom.com | Pan, Zhong-Hua (Suzhou University, Suzhou, P. R. China) | Zheng, Xiao-Jian (Suzhou University, Suzhou, P. R. China) | Xue, Ren-Yu (Suzhou University, Suzhou, P. R. China) | Cao, Guang-Li (Suzhou University, Suzhou, P. R. China)
Cordyceps, one of the well-known traditional Chinese medicines, consists of the dried fungus C. sinensis growing on the larva of caterpillar. It is commonly used as a tonic of restoring vital body functions. In order to evaluate the pharmacological effects of C. militaris, the anti-oxidation and antiaging effect of cultured C. militaris growing on pupa of silkworm Bombyx mori, were investigated. The results showed that the contents of lipofusin in myocardium were reduced and the SOD activity in the liver were elevated in a dose-dependent manner while no effect was observed for blood GSH-Px activity and liver MDA content in mice perfused with the cultured C. militaris compared to those untreated mice.
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