In vitro Screening of Seaweed Extract on the Proliferation of Mouse Spleen and Thymus Cell
2006
Seo, Y.W. (Korea Maritime University, Busan, Republic of Korea), E-mail: [email protected] | Kang, S.H. (Korea Polar Research Institute, KORDI, Ansan, Republic of Korea) | Lee, H.J. (Korea Maritime University, Busan, Republic of Korea) | Kim, Y.A. (Korea Maritime University, Busan, Republic of Korea) | Youn, H.J. (Inje University, Gimhae, Republic of Korea) | Lee, B.J. (Inje University, Gimhae, Republic of Korea) | Chung, H.S. (Korea Polar Research Institute, KORDI, Ansan, Republic of Korea)
A total number of 31 types of seaweed were assessed with regard to their effects on the proliferation of mouse spleen and thymus cells in a culture, using an MTT reduction assay. Acetone:dichloromethane (1:1) extracts of three seaweed plants: Derbesia marina, Sargassum sp., and Hisikia fuziformis, exhibited significantly positive effects on the survival of mouse spleen and thymus cells in vitro. The acetone:dichloromethane (1:1) extracts of Sargassum sp., in particular, much more potent effects on thymus cell activation than did any of the other types of seaweed.
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