The Effect of Benzene on the Activity of Adenosine Deaminase in Tissues of Rats
2007
Turhan, Ali (Uludag University, Bursa, Turkey) | Dere, Egemen (Uludag University, Bursa, Turkey), E-mail: [email protected]
Swiss Albino (Rat rattus norvegicus) rats were intra-peritoneally injected with a 100 mg kg-¹ dosage of benzene, a toxic and carcinogenic agent widely used for industrial purposes. Changes in the adenosine deaminase (ADA) activity in the liver, kidney and serum of rats were investigated at 0, 2, 4, 8, 16, 32 and 64 h following injection. Serum physiological was administered to each control group. Enzyme activities were measured spectro-photometrically. Our purpose was to further investigations of some diseases caused by benzene, and present evidence of variations in the activity of ADA enzyme effected by benzene.
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