Larval migration inhibition activity of ivermectin, doramectin and ethanol against Anisakis simplex in vitro
2007
Jeon, J.H. (Chungbuk National University, Cheongju, Republic of Korea) | Jee, C.H. (Chungbuk National University, Cheongju, Republic of Korea), E-mail: chjee@cbnu.ac.kr
This experiment has been investigated in order to examine larval migration inhibition activity of ivermectin, doramectin and ethanol against Anisakis simplex (A. simplex) in vitro. A. simplex larvae were obtained from the mackerel acquired from the fish market of Cheongju. They were divided into many groups and placed in culture dishes (40 larvae each) containing RPMI-1640, in the absence or presence of different concentrations of ivermectin, doramectin and ethanol. Ivermectin had a complete inhibition of larval migration at 72 h in all groups (10-300 ㎍/ml).
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