Upregulation of aquaporin 2 and aquaporin 4 in the water-deprived mongolian gerbil (Meriones unguiculatus) kidney
2007
Song, J.H. (Chungnam National University, Daejeon, Republic of Korea) | Kwon, J.S. (Chungnam National University, Daejeon, Republic of Korea) | Kim, Y.H. (Chungnam National University, Daejeon, Republic of Korea) | Park, Y.D. (Youngdong University, Youngdong, Republic of Korea) | Han, K.H. (Ewha Womans University, Seoul, Republic of Korea) | Ryu, S.Y. (Chungnam National University, Daejeon, Republic of Korea) | Jung, J.Y. (Chungnam National University, Daejeon, Republic of Korea), E-mail: jyjung@cnu.ac.kr
Mongolian gerbil (Meriones unguiculatus) has been as an model animal for studing the neurological disease such as stroke and epilepsy because of the congenital incompleteries in Willis circle, as well as the investigation of water metabolism because of the long time-survival in the condition of water-deprived desert condition, compared with other species animal. Aquaporin 2 (AQP2) expressed at the surface of principal cells in collecting duct results from an equilibrium between the AQP2 in intracellular vesicles and the AQP2 on the plasma membrane.
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