The effect of Diazinon on glutathine and Acetylcholinesterase in Tilapia (Oreochromis niloticus)
2007
Elnwishy, N.H. (Suez Canal Univ., Ismaila (Egypt). Biotechnology Research Center) | Ahmed, M.T. (Suez Canal Univ., Ismaila (Egypt). Biotechnology Research Center) | El-Sherif, M.S. | El-Hameed, M.A.
The influence of organophosphorus (OP) Diazinon on glutathione (GSH) content, acetylcholinesterase (ACNE) in Tilapia (Oreochromis niloticus) was studied. Uniform (40 g) male tilapia were divided in 3 replicates for two concentrations (LC33.5 & LC10) for 30 days and compared with control (un- treated) fish. Samples of muscles and liver were randomly taken before fish was transferred to untreated aquaria for 7 days of recovery then similar samples were taken. Results revealed that the in vivo chronic exposure of Tilapia to sub-lethal concentrations of Diazinon for 30 days caused a reduction in total GSH and AChE activity. Both total GSH and AChE activity were increased at the end of the recovery intervals. It was concluded that GSH could be a valuable biomarker to mirror pollutant status in the aquatic systems.
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