Effects of stress following vaccination (BUR-706) against infectious bursal disease in broilers
2000
Rasheed, I. (College of Veterinary Sciences, Lahore (Pakistan))
The project was designed to detect and control vaccination stress, following vaccination with live intermediate type infectious bursal disease virus (IBDV) vaccine administered orally and also its effects on immune response in commercial broiler chicks. Comparative efficacy of aspirin and multivitamins was determined to combat the stress. One hundred and sixty-day old broiler chicks were divided into four groups i.e. A, B, C and D, each group having 40 birds. Group A was kept as control, B was vaccinated but non-medicated; C was given multivitamins along with vaccine for 3 post-vaccination days, and group D was treated with Aspirin for 3 post-vaccination days. Blood samples were collected on days 1st, 14th, 28th and 42nd for detection of antibody titer against IBDV. Blood samples were collected from randomly selected 10 birds of each group after 24, 48 and 72 hours of vaccination for ascertaining the following parameters: heterophil/lymphocyte ratio, estimation of serum biochemical substances (protein, glucose and cholesterol). On day 42, adrenal gland/body weight ratio and pathological lesions in adrenal gland were noted. All effort was also made to ascertain tare economics of flock at the end of the experiment. No significant statistical difference among birds of different groups was noted in the following parameters: heterophil/ lymphocyte ratio, serum biochemical substances and adrenal gland/body weight ratio. Vaccine did not cause detectable stress in broilers. Multivitamin therapy showed positive effects on the immune response and growth traits of the birds.
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