Biological availability of chlortetracyclinium chloride in sheep after administration of Vubivet C prm. a.u.v. in milk and water
2005
Neuschl, J.(Univerzita veterinarskeho lekarstva, Kosice (Slovak Republic) | Nagy, J. | Sokol, J. | Saly, J.
The study presents information about the toxic action of sodium salinomycin in the anticoccidial preparation The standard chlortetracyclinium chloride biological availability and other pharmacokinetic parameters were abserved in adult sheep of the Slovak merino breed after administration of Vubivet C prm. in milk and in water. Both groups were given chlortetracyclinium chloride in Vubivet C prm. a.u.v. preparation in a single dose of 20 mg/kg b.w. The preparation was administered per os in 2% suspension by probe. Chlortetracyclinium chloride concentrations in blood serum were determined chromatographically after 1, 3, 6, 12 and 24 hour. After Vubivet C prm. administration in milk and water indicated that biological availability of Vubivet C prm. administered in milk is 33.79% lower than in water. When the preparation was applied in water the biological half-time of chlortetracyclinium chloride was 8.64 hr and 8.82 hr when applied in milk.
Afficher plus [+] Moins [-]Mots clés AGROVOC
Informations bibliographiques
Cette notice bibliographique a été fournie par Slovak University of Agriculture in Nitra
Découvrez la collection de ce fournisseur de données dans AGRIS