Efficacy of albendazole (Aben-15) against gastro-intestinal strongylid nematodes of naturally acquired infection of meat goats
2005
Arkom Sangvaranond(Kasetsart University. Bangkhen Campus, Bangkok (Thailand). Faculty of Veterinary Medicine. Department of Parasitology) | Sathaporn Jittapalapong(Kasetsart University. Bangkhen Campus, Bangkok (Thailand). Faculty of Veterinary Medicine. Department of Parasitology) | Dachpathon Wongdachkajorn(Kasetsart University. Bangkhen Campus, Bangkok (Thailand)) | Devirat Sritong(Kasetsart University. Bangkhen Campus, Bangkok (Thailand)) | Natipong Lampa(Vet Agritech Co., Ltd., Nonthaburi (Thailand))
Efficacy of albendazole (Aben-15) with two various single dosages (6 mg/kg and 8 mg/kg ) orally against strongylids of goats was determined by faecal egg counting reduction test by using McMaster egg counting technique during April 2004 to January 2005. Thirty three naturally acquired gastro-intestinal nematode infected male and female goats aged between 5 months and 2 years old were used . Experimental animals were mixed breed of Thai native and Anglo-Nubian goats which have a history of being treated with albendazole or other benzimidazole anthelminthics for deworming prior to this study. Goats were randomly divided into 3 groups : 10 control untreated goats, 11 albendazole (6 mg/kg ) treated goats and 12 albendazole (8 mg/kg ) treated goats. Efficacy of each dosage against strongylids was the highest during 3-7 days after treatment (94 percent at 6 mg/kg and 88-90 percent at 8 mg/kg) then efficacies were declined gradually. At the dosage of 6 mg/kg, albendazole had 50 percent and 27.5 percent efficacy against goat strongylids at 1 and 2 month post-treatment, respectively and with the dosage of 8 mg/kg, albendazole had 69.4 percent, 70.6 percent and 49.8 percent efficacy at 2 week , 1 and 2 month post-treatment, respectively. From statistical analysis ,albendazole at the dosage of 8 mg/kg could reduce number of strongylid eggs longer than those of 6 mg/kg (p LT 0.05). Number of strongylid eggs in goat faeces in control group during experiment were higher than those at day 0. Side effects of albendazole (Aben-15) in experimental goats were not found.
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