Intestinal microbiota and HIV-1 infection
2007
Trindade, E. B. S. M.(Federal University of Santa Catarina Department of Nutrition Health Sciences Center) | Souza, L. R.(São Paulo State University Botucatu School of Medicine Department of Tropical Diseases) | Lopes, C. A. M.(São Paulo State University Botucatu Institute of Biosciences Department of Microbiology and Immunology) | Pereira, P. C. M.(São Paulo State University Botucatu School of Medicine Department of Tropical Diseases)
The intestinal microbiota consists of a qualitatively and quantitatively diverse range of microorganisms dynamically interacting with the host. It is remarkably stable with regard to the presence of microorganisms and their roles which, however, can be altered due to pathological conditions, diet composition, gastrointestinal disturbances and/or drug ingestion. The present review aimed at contributing to the discussion about changes in the intestinal microbiota due to HIV-1 infection, focusing on the triad infection-microbiota-nutrition as factors that promote intestinal bacterial imbalance. Intestinal microbiota alterations can be due to the HIV-1 infection as a primary factor or the pharmacotherapy employed, or they can be one of the consequences of the disease.
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